Jain Nilam, Gutte Rameshwar, Jadhav Pinanky, Khopkar Uday
Department of Dermatology, Seth GS Medical College and King Edward Memorial Hospital, Mumbai, India.
Indian J Dermatol Venereol Leprol. 2012 Jan-Feb;78(1):82-4. doi: 10.4103/0378-6323.90951.
Lymphomatoid papulosis has been classically described as a chronic, recurrent and self-healing papulonecrotic or papulonodular skin eruption, which is clinically benign and histopathologically malignant. The histologic characteristics of lymphomatoid papulosis are suggestive of a cluster of differentiation 30+ (CD30+) malignant lymphoma, and it is best regarded as a low grade cutaneous T cell lymphoma (CTCL). We hereby report a case of granulomatous and eccrinotropic lymphomatoid papulosis in a 40- year-old male. There was no systemic involvement. The patient was treated with low dose oral methotrexate with good response.
淋巴瘤样丘疹病传统上被描述为一种慢性、复发性且可自愈的丘疹坏死性或丘疹结节性皮肤疹,其临床过程为良性,但组织病理学表现为恶性。淋巴瘤样丘疹病的组织学特征提示为一群分化簇30阳性(CD30+)的恶性淋巴瘤,最好将其视为一种低级别皮肤T细胞淋巴瘤(CTCL)。我们在此报告一例40岁男性的肉芽肿性和向小汗腺性淋巴瘤样丘疹病。无全身受累情况。该患者接受低剂量口服甲氨蝶呤治疗,反应良好。