Daniś J, Nosálová V, Cerný J
Chirurgische Klinik, Instituts für Arztliche Fortbildung, Bratislava.
Z Exp Chir Transplant Kunstliche Organe. 1990;23(1):37-9.
The influence of the proximal selective vagotomy (PSV) on the origin and the extent of experimental gastric ulcer were investigated in rats. The lesions of the gastric mucosa were caused in three groups: by stress through swimming-test, by application of phenylbutazone, and by ischemia (ligature of the left gastric and the right gastroepiploic vessels). The PSV practised a protective influence on the pharmacodynamic etiology, however, not on the stress ulcer. The areas of the ischemic gastric ulcers were larger on an average of 40% after PSV than in the control animals. The difference was not statistically significant. In case the PSV caused besides hyposecretion and hypo-acidity even passive hyperemia caused in the denervated part of the stomach then these did not produce any sufficient defence against the origin of stress ulcers and ischemic lesions.
在大鼠中研究了近端选择性迷走神经切断术（PSV）对实验性胃溃疡的发生及范围的影响。将三组大鼠的胃黏膜造成损伤：通过游泳试验产生应激、应用保泰松以及造成缺血（结扎胃左动脉和胃网膜右动脉）。PSV对药物动力学病因引起的胃溃疡有保护作用，但对应激性溃疡无效。PSV术后，缺血性胃溃疡的面积平均比对照动物大40%。差异无统计学意义。如果PSV除了导致分泌减少和胃酸缺乏外，还使胃去神经支配部分出现被动性充血，那么这些情况并不能对应激性溃疡和缺血性损伤的发生产生足够的防御作用。
