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魁北克省首次急性心肌梗死后,社会经济贫困和居住地对冠状动脉血运重建和死亡率的影响。

Impact of socioeconomic deprivation and area of residence on access to coronary revascularization and mortality after a first acute myocardial infarction in Québec.

机构信息

Institut national de santé publique du Québec, Québec City, Québec, Canada.

出版信息

Can J Cardiol. 2012 Mar-Apr;28(2):169-77. doi: 10.1016/j.cjca.2011.10.009. Epub 2011 Dec 24.

Abstract

BACKGROUND

Socioeconomic status (SES) and area of residence are known to impact access to invasive cardiac procedures. Low SES adversely affects long-term mortality after acute myocardial infarction (AMI). Most of the data were derived from private healthcare systems. Our objectives were to evaluate the effects of SES and area of residence on access to coronary angiography, revascularization and mortality after a first AMI in a publicly-funded healthcare system with a high supply of catheterization facilities.

METHODS

Québec administrative databases were used to identify all patients with a first AMI between 1997 and 2001. The SES was determined with the population deprivation index, which has 2 dimensions: material and social. Six-month access to angiography, revascularization and 1-year mortality were considered in proportional hazards survival regression analyses measuring the effect of deprivation and the geographical area of residence, accounting for several other covariates.

RESULTS

The study cohort consisted of 50,242 patients. The most materially and socially deprived patients had a 16% (95% confidence interval [CI], 1.08-1.25) and 13% (95% CI, 1.05-1.21) relative increased hazard of dying within 1 year respectively compared with the most privileged subjects. This mortality gradient could not be explained by meaningful differences in access to angiography or revascularization. Geography did not influence access to revascularization procedures.

CONCLUSIONS

Despite universal healthcare system, SES measured with a material and social deprivation index, had significant adverse effect on 1-year mortality after a first AMI. Such findings were not explained by lower access to coronary angiography or revascularization.

摘要

背景

社会经济地位(SES)和居住地区已知会影响获得侵入性心脏程序的机会。低 SES 会对急性心肌梗死(AMI)后的长期死亡率产生不利影响。大多数数据来自私人医疗保健系统。我们的目的是评估 SES 和居住地区对在一个高导管设施供应的公共资助医疗保健系统中首次 AMI 后进行冠状动脉造影、血运重建和死亡率的影响。

方法

使用魁北克行政数据库确定了 1997 年至 2001 年之间首次发生 AMI 的所有患者。SES 通过人口剥夺指数确定,该指数具有两个维度:物质和社会。在比例风险生存回归分析中考虑了 6 个月的血管造影、血运重建和 1 年死亡率,以衡量剥夺和居住地区的地理区域的影响,同时考虑了其他几个协变量。

结果

研究队列包括 50,242 名患者。最物质和社会上贫困的患者在 1 年内死亡的相对风险增加了 16%(95%置信区间 [CI],1.08-1.25)和 13%(95% CI,1.05-1.21),与最富裕的受试者相比。这种死亡率梯度不能用血管造影或血运重建的可衡量差异来解释。地理位置对血运重建程序的获得没有影响。

结论

尽管有全民医疗保健系统,但 SES 用物质和社会剥夺指数来衡量,对首次 AMI 后 1 年的死亡率有显著的不利影响。这种发现不能用冠状动脉造影或血运重建的机会较低来解释。

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