Sukolin G I, Pasportnikova O A
Vestn Dermatol Venerol. 1990(6):60-3.
A four-year-old girl with early congenital lymphedema of the lower limbs in combination with the nail plate involvement (pachyonychia) is described. Such a combination is not characteristic of early lymphedema, it is usually described in late edema of the lower limbs. The described case was a sporadic one in the family. It cannot be excluded that lymphedema development was induced by impaired embryogenesis of the lymph vessels resultant from sulphanilamides intake for severe bronchitis that proband's mother had suffered during pregnancy.
本文描述了一名4岁女童，患有早期先天性下肢淋巴水肿并伴有甲板受累（厚甲症）。这种组合并非早期淋巴水肿的特征，通常见于下肢晚期水肿。所描述的病例在家族中为散发病例。不能排除淋巴水肿的发生是由于先证者母亲在孕期因患严重支气管炎服用磺胺类药物导致淋巴管胚胎发育受损所致。
