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先天性下肢静脉瓣发育不全

Congenital venous valvular aplasia of the lower extremities.

作者信息

Friedman E I, Taylor L M, Porter J M

机构信息

Department of Surgery, Oregon Health Sciences University, Portland, Ore. 97201.

出版信息

Surgery. 1988 Jan;103(1):24-6.

PMID:3336868
Abstract

A 10-year-old girl had bilateral, symmetrical swelling of the lower extremities, which had been present since the age of 1 year. Noninvasive vascular laboratory measurements of the ambulatory venous pressure, venous recovery time, and maximum venous outflow revealed profound bilateral lower extremity venous valvular incompetence. Duplex imaging of the veins of the lower extremities demonstrated no evidence of thrombosis, and no venous valves could be imaged. On phlebography, the patient was found to have no venous valves in the superficial and deep systems of the leg. We conclude that congenital absence of the venous valves of the lower extremities is almost certainly underdiagnosed and that the vascular laboratory can accurately and easily differentiate between lymphedema and venous valvular imcompetence. Such differentiation may have therapeutic implications.

摘要

一名10岁女孩自1岁起双下肢出现双侧对称性肿胀。对其动态静脉压、静脉恢复时间和最大静脉流出量进行的非侵入性血管实验室测量显示,双侧下肢存在严重的静脉瓣膜功能不全。下肢静脉的双功超声成像未发现血栓形成迹象,也未显示静脉瓣膜。在静脉造影检查中,发现该患者腿部浅静脉和深静脉系统均无静脉瓣膜。我们得出结论,下肢静脉瓣膜先天性缺失几乎肯定未得到充分诊断,并且血管实验室能够准确且轻松地区分淋巴水肿和静脉瓣膜功能不全。这种区分可能具有治疗意义。

相似文献

1
Congenital venous valvular aplasia of the lower extremities.先天性下肢静脉瓣发育不全
Surgery. 1988 Jan;103(1):24-6.
2
[Congenital absence of vein valves of the lower extremities].[先天性下肢静脉瓣膜缺如]
Zhonghua Wai Ke Za Zhi. 1992 Jun;30(6):358-60, 382-3.
3
Congenital aplasia of the deep veins of lower extremities in children: the role of ascending functional phlebography.儿童先天性下肢深静脉缺如:上行性功能性静脉造影的作用
Surgery. 1986 Apr;99(4):414-20.
4
The use of venous pressure measurements and directional doppler recordings in distinguishing between superficial and deep valvular incompetence in patients with deep venous insufficiency.利用静脉压力测量和定向多普勒记录来区分深静脉功能不全患者的浅静脉和深静脉瓣膜功能不全。
Br J Surg. 1973 Apr;60(4):312.
5
Conception of the venous hemodynamics in the lower extremity.下肢静脉血流动力学的概念。
Angiology. 2006 Oct-Nov;57(5):556-63. doi: 10.1177/0003319706293117.
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[Regulation of lymph outflow in postthrombotic venous insufficiency of the lower extremities].[下肢血栓形成后静脉功能不全时淋巴流出的调节]
Khirurgiia (Mosk). 1979 Sep(9):17-20.
7
Congenital angiodysplasia of the superficial venous system of the lower extremities in children.儿童下肢浅表静脉系统先天性血管发育异常
Ann Surg. 1988 Feb;207(2):213-8. doi: 10.1097/00000658-198802000-00017.
8
[Diagnosis of venous disease].[静脉疾病的诊断]
Herz. 2007 Feb;32(1):10-7. doi: 10.1007/s00059-007-2958-3.
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Venous dynamics in leg lymphedema.腿部淋巴水肿中的静脉动力学
Lymphology. 1999 Mar;32(1):11-4.
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Valvular density alone cannot account for sites of chronic venous insufficiency and ulceration in the lower extremity.单独的瓣膜密度不能解释下肢慢性静脉功能不全和溃疡的部位。
Microcirculation. 2001 Oct;8(5):347-54. doi: 10.1038/sj/mn/7800099.

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Mutations in EPHB4 cause human venous valve aplasia.EPHB4 基因突变导致人类静脉瓣膜发育不全。
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Pre-pubertal presentation of peritoneal inclusion cyst associated with congenital lower extremity venous valve agenesis.
青春期前出现的腹膜包涵囊肿伴先天性下肢静脉瓣发育不全。
JSLS. 2011 Apr-Jun;15(2):264-7. doi: 10.4293/108680811X13071180406835.