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本文引用的文献

1
Treatment of juvenile idiopathic arthritis-associated uveitis: challenges and update.幼年特发性关节炎相关性葡萄膜炎的治疗:挑战与更新。
Curr Opin Rheumatol. 2011 Sep;23(5):432-6. doi: 10.1097/BOR.0b013e328349c324.
2
Prevention of flare recurrences in childhood-refractory chronic uveitis: an open-label comparative study of adalimumab versus infliximab.儿童难治性慢性葡萄膜炎发作预防:阿达木单抗与英夫利昔单抗的开放性比较研究。
Arthritis Care Res (Hoboken). 2011 Apr;63(4):612-8. doi: 10.1002/acr.20404.
3
Favourable outcome after cataract surgery with IOL implantation in uveitis associated with juvenile idiopathic arthritis.葡萄膜炎相关幼年特发性关节炎患者行白内障超声乳化摘除联合人工晶状体植入术后的良好结局。
Acta Ophthalmol. 2012 Nov;90(7):657-62. doi: 10.1111/j.1755-3768.2011.02110.x. Epub 2011 Feb 11.
4
Abatacept: a potential therapy in refractory cases of juvenile idiopathic arthritis-associated uveitis.阿巴西普:治疗幼年特发性关节炎相关葡萄膜炎难治病例的一种潜在疗法。
Graefes Arch Clin Exp Ophthalmol. 2011 Feb;249(2):297-300. doi: 10.1007/s00417-010-1523-6. Epub 2010 Oct 5.
5
Long-term ocular complications in aphakic versus pseudophakic eyes of children with juvenile idiopathic arthritis-associated uveitis.幼年特发性关节炎相关性葡萄膜炎儿童无晶状体眼与人工晶状体眼的长期眼部并发症。
Br J Ophthalmol. 2010 Sep;94(9):1145-9. doi: 10.1136/bjo.2009.167379. Epub 2010 Jun 16.
6
Risk of cataract development among children with juvenile idiopathic arthritis-related uveitis treated with topical corticosteroids.儿童幼年特发性关节炎相关葡萄膜炎患者局部皮质类固醇治疗后的白内障发生风险。
Ophthalmology. 2010 Jul;117(7):1436-41. doi: 10.1016/j.ophtha.2009.12.003. Epub 2010 Apr 3.
7
Abatacept for severe anti-tumor necrosis factor alpha refractory juvenile idiopathic arthritis-related uveitis.阿巴西普治疗抗肿瘤坏死因子-α难治性青少年特发性关节炎相关葡萄膜炎。
Arthritis Care Res (Hoboken). 2010 Jun;62(6):821-5. doi: 10.1002/acr.20115.
8
Cataracts and uveitis.白内障和葡萄膜炎。
Discov Med. 2010 Jan;9(44):51-4.
9
Juvenile idiopathic arthritis associated uveitis in adults: a case series.成人幼年特发性关节炎相关性葡萄膜炎:病例系列研究。
Ocul Immunol Inflamm. 2009 Sep-Oct;17(5):330-4. doi: 10.3109/09273940903118626.
10
Uveitis and juvenile idiopathic arthritis: A cohort study.葡萄膜炎与青少年特发性关节炎:一项队列研究。
Clin Ophthalmol. 2007 Dec;1(4):513-8.

儿童幼年特发性关节炎相关性葡萄膜炎的白内障预防和管理。

Prevention and management of cataracts in children with juvenile idiopathic arthritis-associated uveitis.

机构信息

Division of Pediatric Rheumatology, Emory University School of Medicine, Atlanta, GA 30307, USA.

出版信息

Curr Rheumatol Rep. 2012 Apr;14(2):142-9. doi: 10.1007/s11926-011-0229-z.

DOI:10.1007/s11926-011-0229-z
PMID:22201032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3751191/
Abstract

Juvenile idiopathic arthritis (JIA)-associated uveitis can be associated with vision-compromising complications such as cataracts, glaucoma, synechiae, and band keratopathy. Of these, cataracts are one of the most common sequelae of JIA-associated uveitis and can result in significant visual disability. Risk factors for cataracts include posterior synechiae and longstanding ocular inflammation. Prevention of cataract development is crucial through appropriate control of uveitis. However, not all preventive measures are successful, and further management consisting of medical and surgical techniques is often necessary. Various factors should be taken into consideration when deciding on cataract management, including timing of surgery and placement of an intraocular lens. Continued partnership between pediatric rheumatologists and pediatric ophthalmologists can help ensure favorable visual outcomes.

摘要

幼年特发性关节炎(JIA)相关性葡萄膜炎可引起影响视力的并发症,如白内障、青光眼、虹膜粘连和带状角膜病变。其中,白内障是 JIA 相关性葡萄膜炎最常见的后遗症之一,可导致严重的视力障碍。白内障的危险因素包括后粘连和长期眼内炎症。通过适当控制葡萄膜炎,可以预防白内障的发生,这一点至关重要。然而,并非所有预防措施都有效,通常需要进一步的医疗和手术治疗。在决定白内障治疗方案时,应考虑多种因素,包括手术时机和人工晶状体的放置。儿科风湿病医生和儿科眼科医生之间的持续合作可以帮助确保获得良好的视力结果。