Bölter C, Lauckner W
Klinik für Innere Medizin, Universität Rostock.
Zentralbl Gynakol. 1990;112(16):1009-16.
As a result of hormonal changes processes of adaptation of the cardio-vascular system occur during pregnancy. These regulative changes are the basis for the present echo-cardiographic study which was made under standardized conditions with healthy primigravidae (n = 20) compared to nulligravidae (n = 24). Besides blood pressure and heart frequency dimension and volume sizes of the left ventricle (LV) as well as the LV-weight of muscle and the peripheral vascular resistance were analysed. As result significant increases from the 15th to the 35th week of pregnancy (SSW) could be found for the following parameters: heart frequency, arterial blood pressure, endosystolic volume of the left ventricle, cardiac output, left ventricular weight of muscle (p less than 0.01) endosystolic diameter of the left ventricle, enddiastolic volume of the left ventricle and heart index (p less than 0.05). The peripheral resistance was continuously decreased in the course of pregnancy (p less than 0.01). Compared to non-pregnant women the following parameters showed significantly higher values: heart frequency, cardiac output and heart index (p less than 0.01). The peripheral resistance was significantly lower in pregnant women compared to non-pregnant women (p less than 0.01). From the results the conclusion can be drawn that with statistic certainty echocardiography records adaptive processes of the circulation regulation relative to pregnancy and enables a separation in the groups of pregnant and non-pregnant women.
由于激素变化，孕期会发生心血管系统的适应过程。这些调节性变化是本次超声心动图研究的基础，该研究在标准化条件下对健康初产妇（n = 20）与未孕女性（n = 24）进行了比较。除了血压和心率外，还分析了左心室（LV）的尺寸和容积大小、LV的肌肉重量以及外周血管阻力。结果发现，在妊娠第15至35周（SSW）期间，以下参数有显著增加：心率、动脉血压、左心室收缩末期容积、心输出量、左心室肌肉重量（p < 0.01）、左心室收缩末期直径、左心室舒张末期容积和心脏指数（p < 0.05）。孕期外周阻力持续下降（p < 0.01）。与未孕女性相比，以下参数显示出显著更高的值：心率、心输出量和心脏指数（p < 0.01）。与未孕女性相比，孕妇的外周阻力显著更低（p < 0.01）。从结果可以得出结论，超声心动图能够在统计学上确定地记录与妊娠相关的循环调节适应过程，并能够区分孕妇和未孕女性群体。
