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[术前放化疗(XELOX/放疗)治疗伴有腹股沟淋巴结转移的肛管腺癌]

[Preoperative chemoradiation (XELOX/RT) therapy for anal canal adenocarcinoma with the metastasis to inguinal lymph node].

作者信息

Makino Shunichirou, Ide Yoshihito, Murata Kohei

机构信息

Dept. of Surgery, Suita Municipal Hospital.

出版信息

Gan To Kagaku Ryoho. 2011 Nov;38(12):2048-50.

PMID:22202280
Abstract

For a woman with poorly-differentiated anal canal adenocarcinoma in acknowledgment of metastasis to right inguinal lymph node, we gave radiotherapy combined with capecitabine as chemotherapy. Then the next two months, we performed XELOX therapy. Subsequently, we performed laparoscopic rectal amputation+D1 dissection+right groin lymph node dissection. The effect of preoperative chemoradiotherapy and pathological examination of the main tumor was Grade 2. And the right inguinal lymph node showed only a mucous persistence. Capecitabine was given as an adjuvant postoperative treatment and did not show a recurrence for five months after the operation. For a treatment for anal canal adenocarcinoma in acknowledgment of metastasis to inguinal lymph node, preoperative chemoradiotherapy may be effective.

摘要

对于一名确诊为右腹股沟淋巴结转移的低分化肛管腺癌女性患者,我们给予放疗联合卡培他滨进行化疗。接下来的两个月,我们进行了XELOX方案治疗。随后,我们进行了腹腔镜直肠切除术+D1清扫术+右腹股沟淋巴结清扫术。术前放化疗效果及主要肿瘤的病理检查为2级。右腹股沟淋巴结仅显示黏液残留。术后给予卡培他滨作为辅助治疗,术后五个月未出现复发。对于确诊腹股沟淋巴结转移的肛管腺癌治疗,术前放化疗可能有效。

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Inguinal lymph node metastases from rectal adenocarcinoma: a systematic review.直肠腺癌腹股沟淋巴结转移:系统评价。
Tech Coloproctol. 2023 Nov;27(11):969-978. doi: 10.1007/s10151-023-02826-x. Epub 2023 May 26.
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Anal cancer - a review.肛管癌——综述
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