Salati Sajad Ahmad, Al Kadi Azzam
Department of Surgery, College of Medicine, Qassim University, Qassim, Kingdom of Saudi Arabia.
Int J Health Sci (Qassim). 2012 Jun;6(2):206-30. doi: 10.12816/0006000.
Anal cancer accounts for only 1.5% of gastrointestinal malignancies but this disease has shown a steady increase in incidence particularly in HIV positive males. The understanding of pathophysiology and treatment of anal cancer has changed radically over last thirty years. Risk factors have been identified and organ preservation by chemoradiotherapy has become a standard. This article aims to review the clinical presentation, diagnostic evaluation, and treatment options for anal cancer in the light of current literature.
肛管癌仅占胃肠道恶性肿瘤的1.5%，但该疾病的发病率呈稳步上升趋势，尤其是在HIV阳性男性中。在过去三十年里，对肛管癌病理生理学和治疗的认识发生了根本性变化。已确定了危险因素，通过放化疗进行器官保留已成为标准治疗方法。本文旨在根据当前文献综述肛管癌的临床表现、诊断评估和治疗选择。
