Chang-Yun Lu, Yonemura Yutaka, Ishibashi Haruaki, Sako Shouzou, Tsukiyama Goro, Kitai Toshiyuki, Matsuki Nobuo
Dept. of General Surgery, Wang Fang Hospital, Taipei Medical University, Taiwan.
Gan To Kagaku Ryoho. 2011 Nov;38(12):2060-4.
To evaluate the utility of CT of peritoneal carcinomatosis (PC) by comparing preoperative radiological and intraoperative peritoneal cancer index (PCI) scores.
This study collected 76 patients of PC from different disease origins. The sensitivity, specificity and accuracy were calculated in each of the abdominopelvic region, and by tumor histologic type.
An overall sensitivity of CT was 69%. The detection rate was highest in appendix and lowest in stomach group( 84% and 47%, respectively) by the origin of primary disease. There was a lower detection rate (59% vs 79%, p=0.001), and a higher underestimation rate (29% vs 21%, p<0.05) of small bowel lesion compared with overall abdomino-pelvic region. CT predicted an individual regional PCI score accurately in 65%, underestimated in 24%, and overestimated in 11%. CT detection rate in small tumor (<0.5 cm) was 29%, and increased to 97% with nodules size exceeding 5 cm. CT significantly underestimated the clinical PCI value in overall.
The sensitivity of CT in detecting PC was influenced by histologic type, tumor location and size. CT underestimated the clinical PCI score in PC patient.
通过比较术前影像学和术中腹膜癌指数(PCI)评分,评估腹膜癌(PC)CT检查的效用。
本研究收集了76例不同疾病来源的PC患者。计算每个腹盆腔区域以及肿瘤组织学类型的敏感性、特异性和准确性。
CT的总体敏感性为69%。按原发疾病来源,阑尾组的检出率最高,胃组最低(分别为84%和47%)。与整个腹盆腔区域相比,小肠病变的检出率较低(59%对79%,p = 0.001),低估率较高(29%对21%,p < 0.05)。CT准确预测个体区域PCI评分的比例为65%,低估的比例为24%,高估的比例为11%。小肿瘤(<0.5 cm)的CT检出率为29%,结节大小超过5 cm时增至97%。总体而言,CT显著低估了临床PCI值。
CT检测PC的敏感性受组织学类型、肿瘤位置和大小的影响。CT低估了PC患者的临床PCI评分。