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Sildenafil therapy for bronchopulmonary dysplasia: not quite yet.

作者信息

Farrow K N, Steinhorn R H

出版信息

J Perinatol. 2012 Jan;32(1):1-3. doi: 10.1038/jp.2011.158.

DOI:10.1038/jp.2011.158
PMID:22202953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3907117/
Abstract
摘要

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Sildenafil therapy for bronchopulmonary dysplasia: not quite yet.西地那非治疗支气管肺发育不良:尚未实现。
J Perinatol. 2012 Jan;32(1):1-3. doi: 10.1038/jp.2011.158.
2
Sildenafil citrate, bronchopulmonary dysplasia and disordered pulmonary gas exchange: any benefits?枸橼酸西地那非、支气管肺发育不良和肺气体交换紊乱:有获益吗?
J Perinatol. 2012 Jan;32(1):64-9. doi: 10.1038/jp.2011.131. Epub 2011 Sep 22.
3
Sildenafil for pulmonary hypertension complicating bronchopulmonary dysplasia.西地那非治疗支气管肺发育不良合并肺动脉高压
Expert Rev Clin Pharmacol. 2014 Jul;7(4):393-5. doi: 10.1586/17512433.2014.922867. Epub 2014 May 28.
4
The utility of sildenafil in pulmonary hypertension: a focus on bronchopulmonary dysplasia.西地那非在肺动脉高压中的应用:以支气管肺发育不良为重点。
Arch Dis Child. 2013 Aug;98(8):613-7. doi: 10.1136/archdischild-2012-303333. Epub 2013 Apr 26.
5
Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity.超越肺动脉高压:西地那非用于早产儿慢性肺病
Am J Respir Cell Mol Biol. 2013 Feb;48(2):iii-v. doi: 10.1165/rcmb.2012-0441ED.
6
Sildenafil improves clinical and functional status of an elderly postmenopausal female with 'out of proportion' PH associated with left heart disease.西地那非可改善一名患有与左心疾病相关的“不成比例”肺动脉高压的老年绝经后女性的临床和功能状态。
Monaldi Arch Chest Dis. 2013 Dec;80(4):193-4. doi: 10.4081/monaldi.2013.5237.
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Treatment of schistosomiasis-associated pulmonary hypertension.血吸虫病相关性肺动脉高压的治疗。
J Bras Pneumol. 2011 Mar-Apr;37(2):272-6. doi: 10.1590/s1806-37132011000200018.
8
Should we administer sildenafil to patients with obstructive pulmonary disease and pulmonary hypertension? No.我们应该给患有阻塞性肺疾病和肺动脉高压的患者使用西地那非吗?不应该。
Am J Respir Crit Care Med. 2010 Nov 1;182(9):1206; author reply 1206-7. doi: 10.1164/ajrccm.182.9.1206.
9
Temporal trends in use of sildenafil among pediatric patients.儿科患者使用西地那非的时间趋势。
Am J Respir Crit Care Med. 2013 Nov 15;188(10):1269-71. doi: 10.1164/rccm.201301-0159LE.
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The effect of sildenafil on retinopathy of prematurity in very preterm infants.西地那非对极早早产儿视网膜病变的影响。
J Perinatol. 2013 Mar;33(3):218-21. doi: 10.1038/jp.2012.84. Epub 2012 Jul 5.

引用本文的文献

1
Considerations in the management of hypoxemic respiratory failure and persistent pulmonary hypertension in term and late preterm neonates.足月儿和晚期早产儿低氧性呼吸衰竭及持续性肺动脉高压管理中的注意事项。
J Perinatol. 2016 Jun;36 Suppl 2:S12-9. doi: 10.1038/jp.2016.44.
2
Sildenafil attenuates vaso-obliteration and neovascularization in a mouse model of retinopathy of prematurity.西地那非可减轻早产儿视网膜病变模型中的血管闭塞和新生血管形成。
Invest Ophthalmol Vis Sci. 2014 Mar 10;55(3):1493-501. doi: 10.1167/iovs.13-13207.
3
Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension.高氧诱导肺动脉高压小鼠肺动脉环鸟苷酸信号转导紊乱。
Am J Respir Cell Mol Biol. 2014 Feb;50(2):369-78. doi: 10.1165/rcmb.2013-0118OC.
4
Pulmonary hypertension in bronchopulmonary dysplasia.支气管肺发育不良中的肺动脉高压。
Semin Perinatol. 2013 Apr;37(2):124-31. doi: 10.1053/j.semperi.2013.01.009.
5
The pulmonary circulation in neonatal respiratory failure.新生儿呼吸衰竭的肺循环。
Clin Perinatol. 2012 Sep;39(3):655-83. doi: 10.1016/j.clp.2012.06.006.

本文引用的文献

1
Intrauterine growth restriction decreases pulmonary alveolar and vessel growth and causes pulmonary artery endothelial cell dysfunction in vitro in fetal sheep.宫内生长受限减少肺肺泡和血管生长,并导致体外胎儿羊肺动脉内皮细胞功能障碍。
Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L860-71. doi: 10.1152/ajplung.00197.2011. Epub 2011 Aug 26.
2
Risk factors for pulmonary artery hypertension in preterm infants with moderate or severe bronchopulmonary dysplasia.早产儿中伴有中重度支气管肺发育不良的肺动脉高压的危险因素。
Neonatology. 2012;101(1):40-6. doi: 10.1159/000327891. Epub 2011 Jul 26.
3
Long-term treatment with sildenafil citrate in pulmonary arterial hypertension: the SUPER-2 study.肺动脉高压患者长期应用枸橼酸西地那非治疗:SUPER-2 研究。
Chest. 2011 Nov;140(5):1274-1283. doi: 10.1378/chest.10-0969. Epub 2011 May 5.
4
Nutrition of preterm infants in relation to bronchopulmonary dysplasia.早产儿营养与支气管肺发育不良的关系。
BMC Pulm Med. 2011 Feb 3;11:7. doi: 10.1186/1471-2466-11-7.
5
Pulmonary hypertension in preterm infants with bronchopulmonary dysplasia.支气管肺发育不良早产儿的肺动脉高压。
Korean Circ J. 2010 Mar;40(3):131-6. doi: 10.4070/kcj.2010.40.3.131. Epub 2010 Mar 24.
6
Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease.骨髓基质细胞减轻新生小鼠慢性肺病模型中的肺损伤。
Am J Respir Crit Care Med. 2009 Dec 1;180(11):1122-30. doi: 10.1164/rccm.200902-0242OC. Epub 2009 Aug 27.
7
Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury.西地那非可减轻新生儿高氧性肺损伤中的肺部炎症和纤维蛋白沉积、死亡率及右心室肥厚。
Respir Res. 2009 Apr 29;10(1):30. doi: 10.1186/1465-9921-10-30.
8
Effects of long-term sildenafil treatment for pulmonary hypertension in infants with chronic lung disease.长期使用西地那非治疗慢性肺病婴儿肺动脉高压的效果。
J Pediatr. 2009 Mar;154(3):379-84, 384.e1-2. doi: 10.1016/j.jpeds.2008.09.021. Epub 2008 Oct 31.
9
Nonventilatory strategies for prevention and treatment of bronchopulmonary dysplasia--what is the evidence?预防和治疗支气管肺发育不良的非通气策略——证据是什么?
Neonatology. 2008;94(3):150-9. doi: 10.1159/000143719. Epub 2008 Aug 1.
10
The IUGR newborn.小于胎龄儿新生儿
Semin Perinatol. 2008 Jun;32(3):219-24. doi: 10.1053/j.semperi.2007.11.003.