Matias-Guiu J, Bolumar F, Martin R, Insa R, Casquero P, Moltó J M, Calatayud E, Aranaz J
Department of Neurology, Hospital Virgen de los Lirios, Alcoy, Spain.
Acta Neurol Scand. 1990 Jun;81(6):479-83. doi: 10.1111/j.1600-0404.1990.tb01003.x.
Alcoy is a defined health region in eastern Spain, at 3 degrees E-38 degrees N, with a single neurology department and includes 33 towns with a total population of 133,915 inhabitants. We have evaluated the prevalence and incidence of multiple sclerosis (MS) by analysing this region. Six new cases have been detected (2.24/100,000/year) and the prevalence rate was 17.17/100,000, the highest in Spain at the moment. However, we found an irregular distribution in the different towns in so far that 15 of our 23 patients lived in a particular subregion, which means a prevalence of 44.59/100,000. Our study shows that the area of Alcoy is a medium MS risk region according to the thesis of Kurzke, although high MS areas may be found, thus confirming that MS distribution in southern Europe is not uniform.
阿尔科伊是西班牙东部一个特定的健康区域，位于东经3度至北纬38度之间，设有一个神经内科部门，涵盖33个城镇，总人口为133,915人。我们通过分析该区域评估了多发性硬化症（MS）的患病率和发病率。已检测到6例新病例（2.24/100,000/年），患病率为17.17/100,000，是目前西班牙最高的。然而，我们发现不同城镇存在分布不均的情况，因为我们的23名患者中有15名居住在一个特定的子区域，这意味着患病率为44.59/100,000。我们的研究表明，根据库尔茨克的理论，阿尔科伊地区是中度MS风险区域，尽管可能存在高MS区域，从而证实了MS在南欧的分布并不均匀。
