Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK.
Eur J Pediatr. 2012 May;171(5):843-6. doi: 10.1007/s00431-011-1661-9. Epub 2011 Dec 28.
Data on the effects of a prolonged inflation time during the resuscitation of very prematurely born infants are limited; one study showed no effect, and in another, although lower bronchopulmonary dysplasia (BPD) rates were seen, that effect could have been due to the prolonged inflation time, the positive end expiratory pressure applied or the combination of the two. The aims of our study were to assess the length of inflation times used during face mask and t-piece resuscitation of prematurely born infants in the labour suite and determine whether prolonged inflations led to longer inflation flow times. A respiration monitor (NM3 respiratory profile monitor) was used to record flow, airway pressure and tidal volume changes. The first five inflations for each baby were analysed. Forty prematurely born infants (median gestational age 30, range 26-32 weeks) were examined. Their median inflation pressure was 17.6 (range 12.2-27.4) cm H2O, inflation time 0.89 (range 0.33-2.92) s, expiratory tidal volume 1.01 (range 0.02-11.41) ml/kg and inflation flow time 0.11 (range 0.04-0.54) s. There was no significant relationship between the inflation time and the inflation flow time, but there was a significant relationship between the inflation pressure and the inflation flow time (p = 0.024).
These results suggest that prolonging inflation times during face mask resuscitation of prematurely born infants would not improve ventilation as prolonged inflation did not lead to longer inflation flow times.
评估在产房使用面罩和 T 型管复苏早产儿时的充气时间长度,并确定延长充气是否会导致充气流量时间延长。使用呼吸监测仪(NM3 呼吸描记器)记录流量、气道压力和潮气量变化。分析每个婴儿的前五次充气。
四十名早产儿(中位胎龄 30 周,范围 26-32 周)。
他们的中位充气压力为 17.6(12.2-27.4)cmH2O,充气时间 0.89(0.33-2.92)s,呼气潮气量 1.01(0.02-11.41)ml/kg,充气流量时间 0.11(0.04-0.54)s。充气时间与充气流量时间之间无显著关系,但充气压力与充气流量时间之间存在显著关系(p=0.024)。
这些结果表明,在早产儿使用面罩复苏期间延长充气时间不会改善通气,因为延长充气不会导致更长的充气流量时间。