T 细胞和 B 细胞在动脉粥样硬化中的作用：潜在的临床意义。
The role of T and B cells in atherosclerosis: potential clinical implications.
机构信息
Cardiac and Vascular Sciences, Division of Clinical Sciences, St. George's University of London, Cranmer Terrace, SW17 0RE, London, UK.
出版信息
Curr Pharm Des. 2011 Dec;17(37):4159-71. doi: 10.2174/138161211798764834.
The chronic inflammation process that characterises atherosclerosis involves both the innate and adaptive arms of the immune system. Several lines of evidence have recently highlighted pivotal roles for T and B lymphocytes - cells that belong to the adaptive immune system - in the development and progression of atherosclerosis. In this review, we summarise the current knowledge on the roles of adaptive immune responses in atherosclerosis and present our views on how a better understanding of these immune mechanisms could shape future therapies to slow down or even prevent this disease.
动脉粥样硬化的慢性炎症过程涉及固有免疫和适应性免疫系统。最近有几条证据线强调了 T 和 B 淋巴细胞（属于适应性免疫系统的细胞）在动脉粥样硬化的发生和发展中的关键作用。在这篇综述中，我们总结了适应性免疫反应在动脉粥样硬化中的作用的现有知识，并提出了我们的观点，即更好地了解这些免疫机制如何塑造未来的治疗方法，以减缓甚至预防这种疾病。
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