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作物基因组学:进展与应用。

Crop genomics: advances and applications.

机构信息

Department of Agronomy and Plant Genetics, University of Minnesota, St Paul, Minnesota 55108, USA.

出版信息

Nat Rev Genet. 2011 Dec 29;13(2):85-96. doi: 10.1038/nrg3097.

Abstract

The completion of reference genome sequences for many important crops and the ability to perform high-throughput resequencing are providing opportunities for improving our understanding of the history of plant domestication and to accelerate crop improvement. Crop plant comparative genomics is being transformed by these data and a new generation of experimental and computational approaches. The future of crop improvement will be centred on comparisons of individual plant genomes, and some of the best opportunities may lie in using combinations of new genetic mapping strategies and evolutionary analyses to direct and optimize the discovery and use of genetic variation. Here we review such strategies and insights that are emerging.

摘要

许多重要作物的参考基因组序列的完成以及高通量重测序的能力为我们加深对植物驯化历史的理解和加速作物改良提供了机会。这些数据和新一代的实验与计算方法正在改变作物植物比较基因组学。未来的作物改良将以个体植物基因组的比较为中心,其中一些最佳机会可能在于利用新的遗传图谱策略和进化分析的组合来指导和优化遗传变异的发现和利用。在此,我们综述了正在出现的此类策略和见解。

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