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与针对血小板特异性抗原Yuk(a)致敏相关的新生儿同种免疫性血小板减少性紫癜

Neonatal alloimmune thrombocytopenic purpura associated with sensitization against the platelet-specific antigen Yuk(a).

作者信息

Matsuda T, Yonaha H, Azuma E, Sakurai M, Imai S

机构信息

Department of Pediatrics, Yonaha Hospital, Mie, Japan.

出版信息

Am J Hematol. 1990 Nov;35(3):199-202. doi: 10.1002/ajh.2830350311.

DOI:10.1002/ajh.2830350311
PMID:2220764
Abstract

We report a Japanese newborn who developed alloimmune thrombocytopenia by the antibodies to the newly discovered platelet antigen Yuk(a). The infant recovered uneventfully in 10 days without specific treatment. Antiplatelet alloantibodies in the patient were IgG class detected by mixed passive hemagglutination (MPHA). Family study showed that Yuk(a) antigen was inherited as an autosomal dominant trait. Cases with Yuk(a)-associated alloimmune thrombocytopenia are reviewed.

摘要

我们报告了一名日本新生儿，其因针对新发现的血小板抗原Yuk(a)的抗体而发生同种免疫性血小板减少症。该婴儿未经特殊治疗，于10天内顺利康复。通过混合被动血凝试验（MPHA）检测到患者体内的抗血小板同种抗体为IgG类。家族研究表明，Yuk(a)抗原以常染色体显性性状遗传。本文对与Yuk(a)相关的同种免疫性血小板减少症病例进行了综述。

相似文献

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Neonatal alloimmune thrombocytopenic purpura associated with sensitization against the platelet-specific antigen Yuk(a).与针对血小板特异性抗原Yuk(a)致敏相关的新生儿同种免疫性血小板减少性紫癜
Am J Hematol. 1990 Nov;35(3):199-202. doi: 10.1002/ajh.2830350311.
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Neonatal alloimmune thrombocytopenic purpura induced by anti-Bak(a): a case report and review of the literature.抗Bak(a)诱导的新生儿同种免疫性血小板减少性紫癜：一例报告并文献复习
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Perinatal intracranial hemorrhage due to severe neonatal alloimmune thrombocytopenic purpura (NAITP) associated with anti-Yukb (HPA-4a) antibodies.由于与抗Yukb（HPA-4a）抗体相关的严重新生儿同种免疫性血小板减少性紫癜（NAITP）导致的围产期颅内出血。
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The alloimmune thrombocytopenias: neonatal alloimmune thrombocytopenic purpura and post-transfusion purpura.同种免疫性血小板减少症：新生儿同种免疫性血小板减少性紫癜和输血后紫癜。
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