Fan Chao, Ma Jia, Zhang Hong-ke, Gao Rui, Li Jian-hui, Yu Liang, Wu Zheng, Lv Yi
Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an 710061, China.
Chin Med Sci J. 2011 Sep;26(3):182-9. doi: 10.1016/s1001-9294(11)60046-1.
To explore the feasibility and efficiency of a novel magnetic compression anastomats (MCAs) in intestinal anastomosis.
A total of 36 male mongrel canines underwent intestinal anastomosis using traditional hand-sewn (n=18) or a novel MCAs (n= 18). We compared the anastomosis time, postoperative complications, bursting strength of anastomoses, gross appearance, and pathology between two groups at each timepoint of follow-up.
The mean anastomosis time with MCAs was significantly less than that with hand-sewn (8.50 +/- 1.95 vs. 31.1 +/- 4.32 minutes, P<0.001). The blood stools and intussusceptions occurred in both groups during follow-up period. Only 1 mongrel canine receiving intestinal anastomosis by MCAs experienced anastomotic leakage. The average bursting pressure of anastomoses obtained from mongrel canines undergoing intestinal anastomosis by MCAs was significantly higher than that by traditional hand-sewn at 1 week's follow-up time (P<0.05). Gross appearance of the anastomoses constructed by MCAs was relatively smoother and flatter. Pathological evalution of anastomoses revealed that general inflammation was greater in hand-sewn anastomoses than magnetic anastomosis.
The magnetic compression anastomat is a safe and effective device of sutureless intestinal anastomosis in canine models.
探讨新型磁性压缩吻合器（MCAs）在肠吻合术中的可行性和效率。
总共36只雄性杂种犬接受肠吻合术，其中18只采用传统手工缝合，18只采用新型MCAs。我们在随访的每个时间点比较了两组之间的吻合时间、术后并发症、吻合口破裂强度、大体外观和病理学情况。
使用MCAs的平均吻合时间明显少于手工缝合（8.50±1.95对31.1±4.32分钟，P<0.001）。随访期间两组均出现便血和肠套叠。仅1只接受MCAs肠吻合术的杂种犬发生吻合口漏。在随访1周时，接受MCAs肠吻合术的杂种犬的吻合口平均破裂压力明显高于传统手工缝合（P<0.05）。MCAs构建的吻合口大体外观相对更平滑、更平整。吻合口的病理学评估显示，手工缝合吻合口的一般炎症比磁性吻合更严重。
在犬模型中，磁性压缩吻合器是一种安全有效的无缝合肠吻合装置。
