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一种用于无缝合羊膜贴片治疗急性眼表烧伤的改良睑球粘连环。

A modified symblepharon ring for sutureless amniotic membrane patch to treat acute ocular surface burns.

作者信息

Liang Xuanwei, Liu Zhiping, Lin Ying, Li Naiyang, Huang Minghai, Wang Zhichong

机构信息

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China.

出版信息

J Burn Care Res. 2012 Mar-Apr;33(2):e32-8. doi: 10.1097/BCR.0b013e318239f9b9.

Abstract

The objective of this study is to evaluate a sutureless technique by using a modified symblepharon ring to fix an amniotic membrane (AM) patch on the ocular surface to treat acute ocular burns. Seventy-five patients with acute ocular burns of total 75 eyes graded III to VI were enrolled in this study. They were randomly divided into two groups. Thirty-nine eyes received the sutureless AM patch with a modified symblepharon ring, and the other 36 eyes underwent the conventional sutured AM patch as control. The time and the rate of epithelialization, corneal neovascularization, and complications were recorded. Both the operation time and the time to epithelial closure in the sutureless group were much shorter than that in the suture group (P < .01). The rate of reepithelialization in the sutureless group was higher than in the suture group (P < .05). The rate of the vascularization and symblepharon were lower in the sutureless group than in the suture group (P < .05). The conjunctival sac contraction occurred only in the eyes with grade V and VI in the sutureless group and was later than in the suture group (P < .05). This modified method is simple, minimally invasive, free from trauma, and more effective compared with controls.

摘要

本研究的目的是评估一种无缝合技术,该技术通过使用改良的睑球粘连环将羊膜(AM)贴片固定在眼表来治疗急性眼烧伤。75例共75只眼的急性眼烧伤患者,烧伤程度为III至VI级,纳入本研究。他们被随机分为两组。39只眼接受使用改良睑球粘连环的无缝合AM贴片治疗,另外36只眼作为对照接受传统的缝合AM贴片治疗。记录上皮化时间、角膜新生血管形成情况及并发症。无缝合组的手术时间和上皮闭合时间均明显短于缝合组(P < 0.01)。无缝合组的再上皮化率高于缝合组(P < 0.05)。无缝合组的血管化和睑球粘连发生率低于缝合组(P < 0.05)。无缝合组仅在V级和VI级眼出现结膜囊收缩,且晚于缝合组(P < 0.05)。与对照组相比,这种改良方法简单、微创、无创伤且更有效。

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