Soleimani Mohammad, Naderan Morteza
Ocular Trauma and Emergency Department, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Clin Ophthalmol. 2020 Sep 15;14:2687-2699. doi: 10.2147/OPTH.S235873. eCollection 2020.
Ocular chemical burns are absolute ophthalmic emergencies and require immediate management to minimize devastating sequelae. Management of alkali and acid burns is started at the scene of the accident by copious irrigation. Treatment is directed at improving epithelial integrity and stromal stability, reduction of undue inflammation, and prevention or timely management of complications. To ascertain the best possible outcome, numerous biological medications and surgical interventions have been merged into conventional therapeutic regimens. These include autologous and umbilical cord serum preparations, platelet-rich plasma, amniotic membrane transplantation, limbal stem-cell transplantation, and anti-angiogenic agents.
眼部化学伤是绝对的眼科急症，需要立即进行处理以尽量减少严重的后遗症。碱烧伤和酸烧伤的处理在事故现场就开始进行大量冲洗。治疗旨在改善上皮完整性和基质稳定性，减轻过度炎症，并预防或及时处理并发症。为了确定可能的最佳治疗效果，许多生物药物和手术干预措施已被纳入传统治疗方案中。这些措施包括自体血清和脐带血清制剂、富血小板血浆、羊膜移植、角膜缘干细胞移植以及抗血管生成药物。
