Department of Surgery, William Beaumont Hospital, Royal Oak, Michigan, USA.
ASAIO J. 2012 Jan-Feb;58(1):83-7. doi: 10.1097/MAT.0b013e318239f2e9.
Permanently implantable hemodynamic monitors show great promise in providing personalized and cost-efficient care to heart failure patients by providing timely intracardiac pressure data under ambulatory conditions. The data may be used to titrate maintenance therapies and to monitor health status so that more intensive interventions can be planned and performed under optimal conditions. In this pilot study, we present the results of the implantation of a novel wireless, battery-less pressure sensor into the apex of the left ventricle of four dogs for a period of 8 weeks. All animals recovered to a normal state and did not show any clinical signs of cardiac insufficiency or any complications suggestive of thromboembolism. All sensors functioned throughout the implantation period and provided detailed waveforms of ventricular pressure.
永久性植入式血流动力学监测器有望通过在活动条件下提供即时的腔内压力数据,为心力衰竭患者提供个性化和具有成本效益的护理。这些数据可用于滴定维持治疗,并监测健康状况,以便在最佳条件下计划和进行更强化的干预措施。在这项初步研究中,我们介绍了将一种新型无线、无电池压力传感器植入四只狗的左心室心尖部 8 周的结果。所有动物均恢复正常状态,没有任何心力衰竭的临床症状或任何提示血栓栓塞的并发症。所有传感器在整个植入期间均正常工作,并提供了详细的心室压力波形。