基于 Gd-DTPA 的磁共振可见聚合物，用于直接可视化介入设备。

Gd-DTPA-based MR-visible polymer for direct visualization of interventional devices.

机构信息

Department of Electronic Chemistry, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, Yokohama, Japan.

出版信息

Magn Reson Med Sci. 2011;10(4):263-7. doi: 10.2463/mrms.10.263.

DOI:10.2463/mrms.10.263

PMID:22214913

Abstract

We developed a Gd-DTPA (gadolinium(III)-diethylenetriaminepentaacetic acid)-based coating copolymer of hydrophilic and hydrophobic subunits to obtain visibility, hydrophilicity, and durability for passive visualization of catheters used in MR-guided interventions. We then examined a metal-free catheter coated with the polymer in a phantom and in porcine brain tissue ex vivo. Successful visualization of the coated device demonstrated the applicability of the new coating technique for visualizing catheters used in MR-guided interventions.

摘要

我们开发了一种基于 Gd-DTPA（钆（III）-二乙烯三胺五乙酸）的亲水性和疏水性亚单位的涂层共聚物，以获得用于 MR 引导介入的导管的被动可视化的可见性、亲水性和耐久性。然后，我们在体模和猪脑组织中检查了涂有该聚合物的无金属导管。涂覆装置的成功可视化证明了新涂层技术在可视化 MR 引导介入中使用的导管的适用性。