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危地马拉农村地区轮状病毒相关腹泻:24名婴幼儿的纵向研究

Diarrhea associated with rotavirus in rural Guatemala: a longitudinal study of 24 infants and young children.

作者信息

Wyatt R G, Yolken R H, Urrutia J J, Mata L, Greenberg H B, Chanock R M, Kapikian A Z

出版信息

Am J Trop Med Hyg. 1979 Mar;28(2):325-8. doi: 10.4269/ajtmh.1979.28.325.

DOI:10.4269/ajtmh.1979.28.325
PMID:222155
Abstract

A population of 24 infants and young children followed prospectively during the first 3 years of life was studied for the occurrence of rotavirus infection by using enzyme-linked immunosorbent assay to detect virus in stools. Infection with rotavirus was associated with 26 (14.2%) of 183 selected diarrheal episodes. Twenty of the 24 infants and young children had diarrhea associated with rotavirus on at least one occasion and six had two such episodes. Rotavirus infection was documented in over 50% of the dehydrating episodes studied, thus further indicating the importance of rotavirus in this population.

摘要

对24名婴幼儿在生命的头3年进行前瞻性随访,通过酶联免疫吸附测定法检测粪便中的病毒,以研究轮状病毒感染的发生情况。在183次选定的腹泻发作中,26次(14.2%)与轮状病毒感染有关。24名婴幼儿中,有20名至少有一次腹泻与轮状病毒有关,6名有两次此类发作。在所研究的超过50%的脱水发作中记录到轮状病毒感染,这进一步表明轮状病毒在该人群中的重要性。

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