孟加拉国一个农村治疗中心采用口服补液疗法治疗轮状病毒腹泻
Oral rehydration therapy for treatment of rotavirus diarrhoea in a rural treatment centre in Bangladesh.
作者信息
Taylor P R, Merson M H, Black R E, Mizanur Rahman A S, Yunus M D, Alim A R, Yolken R H
出版信息
Arch Dis Child. 1980 May;55(5):376-9. doi: 10.1136/adc.55.5.376.
In November 1977, an enzyme-linked immunosorbent assay for detecting rotavirus antigen was introduced in the laboratory of a rural treatment centre in Bangladesh. During the next 40 days rotavirus without other pathogens was found in the stools of 216 (45%) of 480 children under age 5 years who visited the centre with a gastrointestinal illness. 188 (87%) of these children were treated with oral rehydration alone, using the solution currently recommended by the World Health Organisation, while 28 (13%) also required some intravenous rehydration; there were no deaths. Oral rehydration treatment was judged successful in 205 (95%) of the rotavirus patients and was not associated with any serious side effects. Oral rehydration treatment, with this solution, has been used extensively and successfully in the treatment of enterotoxin-mediated diarrhoea and can also safely be used for treating rotavirus diarrhoea in infants and young children.
1977年11月，孟加拉国一家农村治疗中心的实验室引入了一种检测轮状病毒抗原的酶联免疫吸附测定法。在接下来的40天里，在该中心因胃肠道疾病前来就诊的480名5岁以下儿童中，有216名（45%）儿童的粪便中检测出轮状病毒，未发现其他病原体。其中188名（87%）儿童仅接受了口服补液治疗，使用的是世界卫生组织目前推荐的溶液，而28名（13%）儿童还需要进行一些静脉补液；无死亡病例。在205名（95%）轮状病毒感染患者中，口服补液治疗被判定为成功，且未出现任何严重副作用。这种溶液的口服补液治疗已广泛且成功地用于治疗肠毒素介导的腹泻，也可安全地用于治疗婴幼儿轮状病毒腹泻。
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