Ferrer Calvete J, Ribes Koninckx C, Montero Brens C
Departamento de Pediatría, Hospital Infantil La Fe, Valencia.
An Esp Pediatr. 1990 Jun;32(6):489-91.
The present study is based on the typical dendritic forms of the sweat crystallization from patients with cystic fibrosis (CF). The phenomenon was analyzed in sweat collected by pilocarpine iontophoresis in 26 affected subjects (Homozygotes), 42 heterozygotes and 100 healthy-control subjects. The positive crystallization pattern (dendritic form), became useful in identifying the affected patients in 100% of cases and in differentiating them from the healthy-control subjects (100%, negative crystallization). The positive crystallization pattern was not altered by decreasing the electrolytes concentration in the sweat. This test could be a help to evaluate the diagnosis of cystic fibrosis.
本研究基于囊性纤维化（CF）患者汗液结晶的典型树枝状形态。对通过毛果芸香碱离子电渗疗法收集的汗液进行了分析，涉及26名受影响受试者（纯合子）、42名杂合子和100名健康对照受试者。阳性结晶模式（树枝状形态）在100%的病例中有助于识别受影响的患者，并将他们与健康对照受试者区分开来（100%为阴性结晶）。汗液中电解质浓度降低并不会改变阳性结晶模式。该测试有助于评估囊性纤维化的诊断。
