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心血管疾病及其相关因素的横断面研究。

A cross-sectional study of cardiovascular disease and associated factors.

作者信息

Islami Farhad, Mańczuk Marta, Vedanthan Rajesh, Vatten Lars, Polewczyk Anna, Fuster Valentin, Boffetta Paolo, Zatoński Witold A

机构信息

Tisch Cancer Institute and Institute for Transitional Epidemiology, Mount Sinai School of Medicine, New York, United States.

出版信息

Ann Agric Environ Med. 2011;18(2):255-9.

PMID:22216792
Abstract

OBJECTIVE

Cardiovascular diseases (CVD) are a major cause of mortality and morbidity in Poland. Data on risk factors of CVD in this country are limited. The presented study investigated risk factors of self-reported CVD within the Polish- Norwegian Study (PONS).

METHODS

PONS is an ongoing prospective study in Poland. The data used was provided by 3,853 participants, aged 45-64, during baseline interviews.

RESULTS

Prevalence of chronic diseases among participants was as follows: hypertension, 38.4%; diabetes, 5.9%; and CVD, 11.0%. There was no association between CVD and gender and place of residence. CVD was associated with ever-smoking (OR= 1.25; 95% CI: 1.00-1.55), whereas there was an inverse association with alcohol drinking in the year preceding enrolment in the study (OR= 0.50; 95% CI: 0.39-0.63). CVD was associated with body mass index (BMI), as well as with measures of abdominal adiposity, in the following order: waist to height ratio>waist circumference>waist to hip ratio; however, none of these measures showed a stronger association with CVD than BMI. Both hypertension (OR= 1.33; 95% CI: 1.05-1.68) and diabetes (OR= 1.33; 95% CI: 1.05-1.68) were associated with CVD in adjusted models.

CONCLUSIONS

This study shows the association between several risk factors and prevalence of self-reported CVD and provides information about distribution of those factors among an adult population in Poland. The results of the ongoing PONS study in a prospective setting will provide more accurate risk estimates for the observed associations, as well as risk estimates for other risk factors of CVD, including dietary factors, and attributable risks for various factors.

摘要

目的

心血管疾病(CVD)是波兰死亡和发病的主要原因。该国关于CVD危险因素的数据有限。本研究在波兰-挪威研究(PONS)中调查了自我报告的CVD危险因素。

方法

PONS是波兰一项正在进行的前瞻性研究。所使用的数据由3853名年龄在45 - 64岁的参与者在基线访谈期间提供。

结果

参与者中慢性病的患病率如下:高血压为38.4%;糖尿病为5.9%;CVD为11.0%。CVD与性别和居住地点之间无关联。CVD与曾经吸烟相关(比值比[OR]=1.25;95%置信区间[CI]:1.00 - 1.55),而与研究入组前一年饮酒呈负相关(OR = 0.50;95% CI:0.39 - 0.63)。CVD与体重指数(BMI)以及腹部肥胖指标相关,顺序如下:腰高比>腰围>腰臀比;然而,这些指标与CVD的关联均未强于BMI。在调整模型中,高血压(OR = 1.33;95% CI:1.05 - 1.68)和糖尿病(OR = 1.33;95% CI:1.05 - 1.68)均与CVD相关。

结论

本研究显示了几种危险因素与自我报告的CVD患病率之间的关联,并提供了这些因素在波兰成年人群中的分布信息。正在进行的PONS前瞻性研究结果将为观察到的关联提供更准确的风险估计,以及CVD其他危险因素(包括饮食因素)的风险估计和各种因素的归因风险。

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