Merino Paulina M, Codner Ethel, Cassorla Fernando
Institute of Maternal and Child Research, School of Medicine, University of Chile, Chile.
Arq Bras Endocrinol Metabol. 2011 Nov;55(8):590-8. doi: 10.1590/s0004-27302011000800013.
Polycystic ovarian syndrome (PCOS) is a lifelong disorder characterized by hyperandrogenism and ovulatory dysfunction, with a wide spectrum of clinical symptoms and signs. Three different sets of diagnostic criteria have been established in order to define this disease in adult women, but there is controversy regarding the use of these criteria in adolescence. During puberty, the adult criteria for ovulatory dysfunction does not seem applicable, because an irregular menstrual pattern and a decreased ovulatory rate is a physiologic event during this period of life. Also, a higher prevalence of polycystic ovarian morphology (PCOM) may be observed during this period, so PCOM is not a useful criterion to define PCOS in young women. These findings suggest that a key factor to diagnose to PCOS during adolescence is hyperandrogenism. In addition, since PCOM is not clearly associated with hyperandrogenism during this period of life, the term "polycystic ovarian syndrome" during adolescence creates confusion and may be misleading.
多囊卵巢综合征（PCOS）是一种终身性疾病，其特征为雄激素过多和排卵功能障碍，伴有广泛的临床症状和体征。为了在成年女性中定义这种疾病，已经建立了三套不同的诊断标准，但在青春期使用这些标准存在争议。在青春期，成人排卵功能障碍的标准似乎并不适用，因为月经周期不规律和排卵率降低在此生命阶段是一种生理现象。此外，在此期间可能观察到多囊卵巢形态（PCOM）的患病率较高，因此PCOM并不是定义年轻女性PCOS的有用标准。这些发现表明，青春期诊断PCOS的关键因素是雄激素过多。此外，由于在此生命阶段PCOM与雄激素过多并无明显关联，青春期的“多囊卵巢综合征”这一术语会造成混淆且可能产生误导。
