State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, P.R. China.
Org Biomol Chem. 2012 Feb 28;10(8):1598-601. doi: 10.1039/c1ob06835k. Epub 2012 Jan 4.
The Rh(I) complex of a monodentate phosphoramidite bearing a primary amine moiety (DpenPhos) has been disclosed to be highly efficient for the asymmetric hydrogenation of a variety of α- or β-acyloxy α,β-unsaturated phosphonates, providing the corresponding biologically important chiral α- or β-hydroxy phosphonic acid derivatives with excellent enantioselectivities (90->99% ee).
含有伯胺部分的单齿膦酰胺配体的 Rh(I) 配合物已被证明对各种α-或β-烷氧基-α,β-不饱和膦酸酯的不对称氢化具有很高的催化活性，能够提供相应的具有重要生物活性的手性α-或β-羟基膦酸衍生物，具有优异的对映选择性（90->99%ee）。
