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Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds.

作者信息

Molnár J, Mándi Y, Holland I B, Schneider G

出版信息

Acta Microbiol Acad Sci Hung. 1977;24(1):1-6.

PMID:22219
Abstract

Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 microgram/ml. The antibacterial compounds deleted at 40-70% frequency the F'lac plasmid of Escherichia coli K12 LE-140.

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