Tarnawska-Pierścińska Małgorzata, Hołody Łukasz, Braziewicz Janusz, Królicki Leszek
Department of Nuclear Medicine, Holycross Cancer Centre, Kielce, Poland.
Nucl Med Rev Cent East Eur. 2011;14(2):105-8. doi: 10.5603/nmr.2011.00024.
Scintigraphy of the skeletal system is performed mainly with the use of 99mTc-MDP. There are other radiopharmaceuticals showing affinity to bone lesions: 99mTc-MIBG, 201Tl, 131I (in the case of papillary or follicular thyroid cancers), and 99mTc (V) DMSA (in the case of medullary cancer). Currently, positron emitted radioisotopes are also used in clinical practice. It seems that 18F-NaF/PET is a highly sensitive and specific modality for detection of metastases and other bone lesions. Certain data concerning the role of 18F-FDG, 18F-choline, or 68Ga-DOTATATE can be found. The aim of this article is to review the role of 18F-NaF and 18F-FDG in diagnosis of bone metastases.
骨骼系统闪烁扫描主要使用99mTc-MDP进行。还有其他对骨病变显示出亲和力的放射性药物：99mTc-MIBG、201Tl、131I（用于乳头状或滤泡状甲状腺癌）以及99mTc(V)DMSA（用于髓样癌）。目前，正电子发射放射性同位素也用于临床实践。18F-NaF/PET似乎是检测转移灶和其他骨病变的一种高度敏感且特异的方法。可以找到一些关于18F-FDG、18F-胆碱或68Ga-DOTATATE作用的相关数据。本文的目的是综述18F-NaF和18F-FDG在骨转移诊断中的作用。
