Paraf F, Py A, Pauly-Laubry C, Camilleri J P
Laboratoire d'Anatomie Pathologique, Hôpital Broussais, Paris.
Arch Anat Cytol Pathol. 1990;38(4):171-9.
Clinical cardiac manifestations are rare in the course of acquired immunodeficiency syndrome (AIDS), but cardiac lesions can be found at autopsy in 60% of cases. Myocardium and pericardium are the most frequently involved. Cardiac involvement in opportunistic infections, Kaposi's sarcoma, and non Hodgkin's malignant lymphomas usually reflects systemic dissemination of the disease. Idiopathic myocarditis and hypertrophic cardiomyopathy may also occur and may be related to human immunodeficiency virus. Dysautonomia and drug-induced cardiac lesions have also been reported. Cardiac involvement of acquired immunodeficiency syndrome in children is characterized by possible lesions of conduction tissue.
临床心脏表现在获得性免疫缺陷综合征(艾滋病)病程中较为罕见,但尸检时60%的病例可发现心脏病变。心肌和心包是最常受累的部位。心脏受累于机会性感染、卡波西肉瘤和非霍奇金恶性淋巴瘤通常反映了疾病的全身播散。特发性心肌炎和肥厚型心肌病也可能发生,且可能与人类免疫缺陷病毒有关。自主神经功能障碍和药物性心脏病变也有报道。儿童获得性免疫缺陷综合征的心脏受累表现为传导组织可能出现病变。