Lanjewar D N, Katdare G A, Jain P P, Hira S K
Department of Pathology, Grant Medical College amd Sir JJ Group of Hospitals, Mumbai.
Indian Heart J. 1998 May-Jun;50(3):321-5.
The spectrum of cardiac lesions in patients with acquired immunodeficiency syndrome in India is not described. To determine the extent of involvement of the heart with this disease, an autopsy study of 52 subjects having acquired immunodeficiency syndrome was carried out. Multiple sections were obtained from different anatomical parts of each heart. Forty-eight of the 52 hearts showed subtle microscopic changes, the most common being myocardial atrophy (48 cases), lymphocytic pericarditis (38 cases), fibrinous pericarditis (1 case), pericardial fibrosis (1 case), lymphocytic myocarditis (29 cases) and myocardial fibrosis (7 cases). Cryptococcosis of the heart was noticed in two cases, while in one case toxoplasmic myocarditis was identified. In only one case clinical presentation of cardiac involvement (pericardial effusion) was noted, which indicates that in spite of the presence of significant pathology in the heart, overt cardiac manifestations are infrequently seen in patients with acquired immunodeficiency syndrome.
印度获得性免疫缺陷综合征患者心脏病变的范围尚无描述。为确定该病累及心脏的程度，对52例获得性免疫缺陷综合征患者进行了尸检研究。从每颗心脏的不同解剖部位获取多个切片。52颗心脏中有48颗显示出细微的微观变化，最常见的是心肌萎缩（48例）、淋巴细胞性心包炎（38例）、纤维素性心包炎（1例）、心包纤维化（1例）、淋巴细胞性心肌炎（29例）和心肌纤维化（7例）。2例发现心脏隐球菌病，1例确诊为弓形虫性心肌炎。仅1例有心脏受累的临床表现（心包积液），这表明尽管心脏存在明显病变，但获得性免疫缺陷综合征患者很少出现明显的心脏表现。
