Samama Margriet, van Poelgeest Mariette
Department of Gynaecology, Sint Franciscus Gasthuis, Rotterdam.
Case Rep Oncol. 2011 Sep;4(3):560-3. doi: 10.1159/000334852. Epub 2011 Dec 2.
Primary malignant lymphomas in the female genital tract are rare. Most cases are non-Hodgkin lymphomas of which diffuse large B-cell lymphomas are most commonly seen. Symptoms are associated with other, more common diseases; therefore, a doctors' delay can be expected. In this case a woman presented with complaints of urinary obstruction due to a large tumour in the pelvic area. A laparotomy was performed. A very large tumour of the uterus was found with adherence to the pelvic wall and urinary bladder. Diagnostic histological examination showed a diffuse large B-cell lymphoma. Treatment with R-CHOP chemotherapy was started shortly after the operation. The treatment of patients with a primary malignant lymphoma of the uterus should be individualized with the following options: surgery, radiotherapy and/or chemotherapy.
女性生殖道原发性恶性淋巴瘤较为罕见。大多数病例为非霍奇金淋巴瘤,其中弥漫性大B细胞淋巴瘤最为常见。症状与其他更常见的疾病相关;因此,可能会出现医生诊断延误的情况。在本病例中,一名女性因盆腔巨大肿瘤出现尿路梗阻症状。进行了剖腹手术。发现一个非常大的子宫肿瘤,与盆腔壁和膀胱粘连。诊断性组织学检查显示为弥漫性大B细胞淋巴瘤。术后不久开始采用R-CHOP化疗。子宫原发性恶性淋巴瘤患者的治疗应个体化,可选择以下方法:手术、放疗和/或化疗。