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血小板浓缩物在气动输送管系统中的输送——它是否有效?

Platelet concentrate transport in pneumatic tube systems--does it work?

机构信息

Maastricht University Medical Centre+, Department of Anaesthesiology and Pain Treatment, University Hospital Maastricht, P. Debyelaan 25, Maastricht, The Netherlands.

出版信息

Vox Sang. 2012 Jul;103(1):79-82. doi: 10.1111/j.1423-0410.2011.01580.x. Epub 2012 Jan 5.

DOI:10.1111/j.1423-0410.2011.01580.x
PMID:22220640
Abstract

Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Optical and impedance aggregation, CD-62, and microparticles changed as a result of storage, but not due to transport. Irradiation lowered platelet function independently. Multiple transport impaired thrombin receptor-activating peptide-induced aggregation. This investigation demonstrates the feasibility of PTS transport. As platelet function depends on storage, it may be more important to transfuse fresh PCs.

摘要

通过气动管道系统(PTS)运输血样可以缩短实验室的周转时间,但可能会影响分析结果。目前尚不清楚其对血小板浓缩物(PC)的影响。本研究比较了单次和多次 PTS 运输与储存和辐照对血小板功能的影响。光学和阻抗聚集、CD-62 和微颗粒由于储存而发生变化,但不是由于运输。辐照会独立降低血小板功能。多次运输会损害凝血酶受体激活肽诱导的聚集。本研究证明了 PTS 运输的可行性。由于血小板功能取决于储存,因此输注新鲜的 PC 可能更为重要。

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