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血液成分通过气动管道系统传输的验证。

Validation of blood components transport through a pneumatic tube system.

作者信息

Garcia Laís Oliveira, Speransa Daniela Michelim Rodriguez, Rodrigues Cristiane Braga, Benites Rosimari Melgarejo, Garcia Mariana Timm, Sekine Leo, Franz Juliana Pires Marafon

机构信息

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.

Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.

出版信息

Hematol Transfus Cell Ther. 2022 Oct-Dec;44(4):519-525. doi: 10.1016/j.htct.2021.07.010. Epub 2021 Nov 16.

DOI:10.1016/j.htct.2021.07.010
PMID:34824032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9605890/
Abstract

INTRODUCTION

Urgent blood component transfusions may be life-saving for patients in hemorrhagic shock. Measures to reduce the time taken to provide these transfusions, such as uncrossmatched transfusion or abbreviated testing, are available. However, transport time is still an additional delay and the use of a pneumatic tube system (PTS) may be an alternative to shorten the transport time of blood components.

OBJECTIVES

To assess pneumatic tube system transportation of blood components based on a validation protocol.

METHODS

Pre- and post-transport quality control laboratory parameters, visual appearance, transport time and temperature of the packed red blood cells (RBCs), thawed fresh plasma (TFP), cryoprecipitate (CR), and platelet concentrate (PC) were evaluated. Parameters were compared between transport via pneumatic tube and courier.

RESULTS

A total of 23 units of RBCs, 50 units of TFP, 30 units of CR and ten units of PC were evaluated. No statistically significant differences were found between pre- and post-transport laboratory results. There was also no difference in laboratory parameters between transport modalities (PTS versus courier). All blood components transported matched regulatory requirements for quality criteria. The temperature during transport remained stable and the transport time via PTS was significantly shorter than the courier's transport time (p < 0.05).

CONCLUSION

The PTS was considered a fast, safe and reliable means of transportation for blood components, also securing quality prerequisites.

摘要

引言

紧急输血对于失血性休克患者可能是救命的。有一些措施可减少输血所需时间,如未交叉配血输血或简化检测。然而,运输时间仍是额外的延迟,而使用气动管道系统(PTS)可能是缩短血液成分运输时间的一种选择。

目的

根据验证方案评估气动管道系统对血液成分的运输情况。

方法

对运输前后的质量控制实验室参数、外观、包装红细胞(RBC)、解冻新鲜血浆(TFP)、冷沉淀(CR)和浓缩血小板(PC)的运输时间及温度进行评估。比较通过气动管道运输和快递运输的参数。

结果

共评估了23单位的RBC、50单位的TFP、30单位的CR和10单位的PC。运输前后的实验室结果之间未发现统计学上的显著差异。运输方式(PTS与快递)之间的实验室参数也无差异。所有运输的血液成分均符合质量标准的监管要求。运输过程中的温度保持稳定,通过PTS的运输时间明显短于快递运输时间(p < 0.05)。

结论

PTS被认为是一种快速、安全且可靠的血液成分运输方式,同时也确保了质量前提条件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a470/9605890/9026f34ae918/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a470/9605890/9026f34ae918/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a470/9605890/9026f34ae918/gr1.jpg

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本文引用的文献

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Asian J Transfus Sci. 2019 Jan-Jun;13(1):3-9. doi: 10.4103/ajts.AJTS_52_18.
2
Effect of Pneumatic Tubing System Transport on Platelet Apheresis Units.气动管道系统运输对血小板单采单位的影响。
Cardiovasc Eng Technol. 2018 Sep;9(3):515-527. doi: 10.1007/s13239-018-0361-2. Epub 2018 May 21.
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Evaluation of the pneumatic tube system for transportation of packed red cell units.用于运输红细胞悬液的气动管道系统评估。
Asian J Transfus Sci. 2015 Jul-Dec;9(2):195-8. doi: 10.4103/0973-6247.154254.
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Hemolysis associated with pneumatic tube system transport for blood samples.与血样气动输送系统相关的溶血。
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