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基于门静脉直径测量和标准肝体积计算对活体供肝右半肝体积的精确估计。

Accurate estimation of living donor right hemi-liver volume from portal vein diameter measurement and standard liver volume calculation.

机构信息

Department of Transplantation and Hepatobiliary Diseases, Lahey Clinic Medical Center, Burlington, MA, USA.

出版信息

Am J Transplant. 2012 May;12(5):1229-39. doi: 10.1111/j.1600-6143.2011.03909.x. Epub 2012 Jan 5.

DOI:10.1111/j.1600-6143.2011.03909.x
PMID:22221803
Abstract

Lee et al. recently published a method for estimating right hemi-liver volume (RHLV) by using bedside ultrasound measurement of right (R) and left (L) portal vein (PV) diameters and Urata's standard liver volume (SLV) formula where RHLV = SLV×[R(2) /(R(2) +L(2) )]. We calculated RHLV by substituting SLV from 15 different published formulas in the worldwide literature. We also modified Lee's method using right anterior (RA) and posterior (RP) where RHLV = SLV×[(RA(2) +RP(2) )/(RA(2) +RP(2) +L(2) )] for donors with unusual PV branching. We compared the calculated RHLV with RHLV estimated with software-assisted CT (SACT) volumetry and actual graft weight after right-lobe donation in 200 right-lobe donors. This study confirmed that accurate estimates of RHLV can be achieved by SACT volumetry or by the simple method of Lee but using the SLV of only 3 of the 15 published formulas (Lin or Vauthey using body weight or body surface area) rather than Urata's. Our modification of the Lee's formula using RA and RP, PV diameters was also accurate and not different from Lee's formula. These simplified formulas may be used for donor screening for graft size adequacy before expensive evaluation proceeds.

摘要

李等人最近发表了一种方法,通过测量右(R)和左(L)门静脉(PV)直径以及使用 Urata 的标准肝体积(SLV)公式来估算右半肝体积(RHLV),其中 RHLV = SLV×[R(2) /(R(2) +L(2) )]。我们通过在全球文献中 15 种不同的已发表公式中替代 SLV 来计算 RHLV。我们还通过使用右前(RA)和后(RP)门静脉分支异常供体的 RHLV = SLV×[(RA(2) +RP(2) )/(RA(2) +RP(2) +L(2) )]修改了 Lee 的方法。我们将计算的 RHLV 与使用软件辅助 CT(SACT)体绘制估算的 RHLV 以及右叶捐献后实际移植物重量进行比较在 200 例右叶供体中。本研究证实,SACT 体绘制或 Lee 的简单方法(但仅使用 15 种已发表公式中的 3 种 SLV(Lin 或 Vauthey 使用体重或体表面积)而不是 Urata 的)可以准确估算 RHLV。我们使用 RA 和 RP、PV 直径对 Lee 公式的修改也是准确的,与 Lee 公式没有区别。这些简化公式可用于在昂贵的评估进行之前进行供体筛选,以确定移植物大小是否合适。

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