Sapin M R, Ambartsumian E F
Arkh Anat Gistol Embriol. 1990 May;98(5):5-10.
Spleens (27) obtained from human corpses (from 1 year up to 85 years) have been investigated. By means of morphometrical grid amount of cells in the periarterial lymphoid muffs (PLM) and in marginal zones (MZ) of the spleen have been counted. In both structures of the white pulp small lymphocytes make the greatest number. Middle lymphocytes in comparison to the small ones are 1.5-4 times less in most of the age groups investigated. Amount of plasma cells is small. The part of reticular cells is 21-46% in MZ and 20-36% in PLM from the total amount of cells. In PLM immediately around the artery tightly packed to each other small lymphocytes are situated. Among small lymphocytes reticular cells are situated. A similar arrangement of cells is kept along the whole thickness of PLM. In MZ distance between cells of the lymphoid line is a little greater than in PLM. To singularly situating reticular cells small and middle lymphocytes are immediate neighbours. Plasma cells, as a rule, occur seldom; either middle lymphocytes, or reticular cells adjoin them. Sometimes, in PLM and MZ macrophages occur; they are situated in the areas free from other cells.
对取自人体尸体（年龄从1岁到85岁）的27个脾脏进行了研究。借助形态测量网格，对脾动脉周围淋巴鞘（PLM）和边缘区（MZ）中的细胞数量进行了计数。在白髓的这两种结构中，小淋巴细胞数量最多。在大多数研究的年龄组中，中型淋巴细胞与小淋巴细胞相比少1.5至4倍。浆细胞数量很少。网状细胞在MZ中的比例占细胞总数的21%至46%，在PLM中占20%至36%。在紧邻动脉的PLM中，小淋巴细胞彼此紧密排列。在小淋巴细胞之间分布着网状细胞。在PLM的整个厚度范围内，细胞都保持着类似的排列方式。在MZ中，淋巴系细胞之间的距离比PLM中的稍大。单个分布的网状细胞紧邻小淋巴细胞和中型淋巴细胞。浆细胞通常很少出现；它们要么与中型淋巴细胞相邻，要么与网状细胞相邻。有时，在PLM和MZ中会出现巨噬细胞；它们位于没有其他细胞的区域。
