在常规临床实践中，针对病程长达15年的类风湿关节炎患者进行目标导向治疗可改善其功能。 - Suppr

Goal-directed therapy for RA in routine practice is associated with improved function in patients with disease duration up to 15 years.

作者信息

Gullick Nicola J, Oakley Stephen P, Zain Amir, Gibson Terence, Jones Tim, Mistlin Alan, Rees Jonathan D, Panayi Gabriel S, Kirkham Bruce W

出版信息

Rheumatology (Oxford). 2012 Apr;51(4):759-61. doi: 10.1093/rheumatology/ker399. Epub 2012 Jan 5.

DOI:10.1093/rheumatology/ker399

PMID:22223707

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3306167/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1768/3306167/978defb48f6c/ker399f1.jpg

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Goal-directed therapy for RA in routine practice is associated with improved function in patients with disease duration up to 15 years.在常规临床实践中，针对病程长达15年的类风湿关节炎患者进行目标导向治疗可改善其功能。

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Which patients with rheumatoid arthritis, spondyloarthritis, or juvenile idiopathic arthritis receive TNF-α antagonists in France? The CORPUS cohort study.在法国，哪些类风湿性关节炎、脊柱关节炎或青少年特发性关节炎患者接受了肿瘤坏死因子-α拮抗剂治疗？CORPUS队列研究。

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Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force.类风湿关节炎达标治疗：国际特别工作组2014年推荐意见更新

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Drug therapy of inflammatory arthritis.炎症性关节炎的药物治疗。

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本文引用的文献

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search.治疗类风湿关节炎的靶向治疗证据：系统文献检索结果。

Ann Rheum Dis. 2010 Apr;69(4):638-643. doi: 10.1136/ard.2009.123976.

Treating rheumatoid arthritis to target: recommendations of an international task force.靶向治疗类风湿关节炎：国际工作组的建议。

Ann Rheum Dis. 2010 Apr;69(4):631-7. doi: 10.1136/ard.2009.123919. Epub 2010 Mar 9.

Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade.类风湿关节炎患者采用甲氨蝶呤单药治疗以及英夫利昔单抗联合甲氨蝶呤治疗并达到不同疾病活动状态时的影像学改变：缓解和肿瘤坏死因子阻断的影响

Ann Rheum Dis. 2009 Jun;68(6):823-7. doi: 10.1136/ard.2008.090019. Epub 2008 Jul 1.

Identification of disease activity and health status cut-off points for the symptom state acceptable to patients with rheumatoid arthritis.确定类风湿关节炎患者可接受的症状状态的疾病活动度和健康状况临界点。

Ann Rheum Dis. 2008 Jul;67(7):967-71. doi: 10.1136/ard.2007.077503. Epub 2007 Oct 26.

Ann Rheum Dis. 2008 Feb;67(2):238-43. doi: 10.1136/ard.2007.071415. Epub 2007 Jul 20.

Disconnect between inflammation and joint destruction after treatment with etanercept plus methotrexate: results from the trial of etanercept and methotrexate with radiographic and patient outcomes.依那西普联合甲氨蝶呤治疗后炎症与关节破坏之间的脱节：依那西普和甲氨蝶呤影像学及患者预后试验结果

Arthritis Rheum. 2006 Oct;54(10):3119-25. doi: 10.1002/art.22143.

Early suppression of disease activity is essential for maintenance of work capacity in patients with recent-onset rheumatoid arthritis: five-year experience from the FIN-RACo trial.早期抑制疾病活动对于近期发病的类风湿关节炎患者维持工作能力至关重要：芬兰类风湿关节炎队列研究（FIN-RACo）的五年经验

Arthritis Rheum. 2005 Jan;52(1):36-41. doi: 10.1002/art.20716.

Retardation of joint damage in patients with early rheumatoid arthritis by initial aggressive treatment with disease-modifying antirheumatic drugs: five-year experience from the FIN-RACo study.通过使用改善病情抗风湿药物进行初始积极治疗延缓早期类风湿关节炎患者的关节损伤：来自芬兰类风湿关节炎注册研究（FIN-RACo）的五年经验

Arthritis Rheum. 2004 Jul;50(7):2072-81. doi: 10.1002/art.20351.

Patients and clinicians have different perspectives on outcomes in arthritis.患者和临床医生对关节炎的治疗结果有不同的看法。

J Rheumatol. 2003 Apr;30(4):877-9.

The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.美国风湿病协会1987年修订的类风湿关节炎分类标准。

Arthritis Rheum. 1988 Mar;31(3):315-24. doi: 10.1002/art.1780310302.

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Goal-directed therapy for RA in routine practice is associated with improved function in patients with disease duration up to 15 years.

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