Savić Živorad N, Soldatović Ivan I, Brajović Milan D, Pavlović Aleksandra M, Mladenović Dušan R, Škodrić-Trifunović Vesna D
Center of Radiology and Magnetic Resonance, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Serbia.
ScientificWorldJournal. 2011;11:1582-90. doi: 10.1100/tsw.2011.147. Epub 2011 Aug 16.
The increased thickness of the carotid wall >1 mm is a significant predictor of coronary and cerebrovascular diseases. The purpose of our study was to assess the agreement between multidetector row computed tomography angiography (MDCTA) in measuring carotid artery wall thickness (CAWT) and color Doppler ultrasound (CD-US) in measuring intimae-media thickness (IMT). Eighty-nine patients (aged 35-81) were prospectively analyzed using a 64-detector MDCTA and a CD-US scanner. Continuous data were described as the mean value ± standard deviation, and were compared using the Mann-Whitney U test. A p value <0.05 was considered significant. Bland-Altman statistics were employed to measure the agreement between MDCTA and CD-US. CAWT ranged from 0.62 to 1.60 mm, with a mean value of 1.09 mm. IMT ranged from 0.60 to 1.55 mm, with a mean value of 1.06 mm. We observed an excellent agreement between CD-US and MDCTA in the evaluation of the common carotid artery thickness, with a bias between methods of 0.029 mm (which is a highly statistically important difference of absolute values [t = 43.289; p < 0.01] obtained by paired T test), and limits of agreement from 0.04 to 0.104. Pearson correlation coefficient was 0.9997 (95% CI 0.9996-0.9998; p < 0.01). We conclude that there is an excellent correlation between CAWT and IMT measurements obtained with the MDCTA and CD-US.
颈动脉壁厚度增加>1mm是冠状动脉和脑血管疾病的重要预测指标。我们研究的目的是评估多排螺旋计算机断层血管造影（MDCTA）测量颈动脉壁厚度（CAWT）与彩色多普勒超声（CD-US）测量内膜中层厚度（IMT）之间的一致性。对89例年龄在35 - 81岁的患者前瞻性地使用64排MDCTA和CD-US扫描仪进行分析。连续数据以平均值±标准差描述，并使用Mann-Whitney U检验进行比较。p值<0.05被认为具有统计学意义。采用Bland-Altman统计量来衡量MDCTA和CD-US之间的一致性。CAWT范围为0.62至1.60mm，平均值为1.09mm。IMT范围为0.60至1.55mm，平均值为1.06mm。我们观察到在评估颈总动脉厚度方面，CD-US与MDCTA之间具有极好的一致性，方法间偏差为0.029mm（通过配对T检验获得的绝对值具有高度统计学意义的差异[t = 43.289；p < 0.01]），一致性界限为0.04至0.104。Pearson相关系数为0.9997（95%CI 0.9996 - 0.9998；p < 0.01）。我们得出结论，MDCTA和CD-US测量的CAWT与IMT之间存在极好的相关性。
