Department of Inorganic Chemistry, University of Almería, Campus de Excelencia Internacional Agroalimentario (ceiA3), La Cañada de San Urbano s/n, Almería.
J Agric Food Chem. 2012 Feb 1;60(4):1042-51. doi: 10.1021/jf2037483. Epub 2012 Jan 18.
Imidacloprid, a systemic insecticide that has a water solubility of 610 mg L(-1), has been formulated in lignin-polyethylene glycol matrices by a melting process. This formulation was coated in a Wurster type fluidized-bed equipment using ethylcellulose and dibutyl sebacate. Imidacloprid has been entrapped, with an entrapment efficiency higher than 87% in all cases. Thermogravimetric analysis, differential scanning calorimetry, and Fourier transformed infrared spectroscopy studies indicate the stability and compatibility of polymers and imidacloprid. Scanning electron microscopy images show a homogeneous film of ethylcellulose in coated formulations. From T(50) values (the time taken for 50% of the active ingredient to be released into water), the release rate of imidacloprid is controlled by changing the thickness of the coating film and modifying its surface properties by adding a plasticizer. T(50) values, ranging from 3.02 to 168.6 h, allow supplying the appropriate amount of imidacloprid in each specific agronomic practice to increase the efficiency of this bioactive material and minimize the risk of environmental pollution.
吡虫啉是一种内吸性杀虫剂，水溶性为 610mg/L，通过熔融过程被制成木质素-聚乙二醇基质。该制剂在 Wurster 型流化床设备中使用乙基纤维素和癸二酸二丁酯进行包衣。吡虫啉的包封效率均高于 87%。热重分析、差示扫描量热法和傅里叶变换红外光谱研究表明聚合物和吡虫啉的稳定性和相容性。扫描电子显微镜图像显示包衣制剂中乙基纤维素的均匀薄膜。从 T(50)值（活性成分有 50%释放到水中所需的时间）来看，通过改变涂层的厚度和通过添加增塑剂来改变其表面性质，可以控制吡虫啉的释放速率。T(50)值范围为 3.02 至 168.6 小时，可以根据每种特定的农业实践提供适量的吡虫啉，从而提高这种生物活性物质的效率并最大程度地降低环境污染的风险。
