Choux C, Vergès B, Isnardon J-P, Rousselet J-M, Douvier S, Sagot P
Service de gynécologie-obstétrique, CHU de Dijon, 6 boulevard Maréchal-de-Lattre-de-Tassigny, Dijon, France.
J Gynecol Obstet Biol Reprod (Paris). 2012 Jun;41(4):383-6. doi: 10.1016/j.jgyn.2011.12.002. Epub 2012 Jan 9.
Pheochromocytomas are rare but potentially lethal tumors responsible for malignant hypertension. They may be encountered by gynecologists and obstetricians. The diagnosis is difficult because it can be mistaken for diseases more frequent like preeclampsia or other pelvic tumors. We report two cases highlighting clinical clues such as labile hypertension, headache, sweating, palpitations and failure to respond to conventional treatment should prompt physicians to screen patients for pheochromocytoma by measuring the 24-hour urinary catecholamines. The surgery must be performed after using an appropriate preoperative treatment, in order not to trigger lethal outcome. During pregnancy, C-section is recommended.
嗜铬细胞瘤虽罕见但可能致命,是恶性高血压的病因。妇产科医生可能会遇到此类病例。由于其可能被误诊为更常见的疾病,如先兆子痫或其他盆腔肿瘤,故诊断困难。我们报告两例病例,强调不稳定高血压、头痛、出汗、心悸等临床线索,以及对传统治疗无反应时,应促使医生通过检测24小时尿儿茶酚胺来筛查嗜铬细胞瘤患者。必须在进行适当的术前治疗后再进行手术,以免引发致命后果。怀孕期间,建议行剖宫产。