Prajapati M S, Patel J B, Modi K, Shah M B
Kalol Institute of Pharmacy, Gujarat University, Kalol, India.
Pharmacogn Rev. 2010 Jan;4(7):85-7. doi: 10.4103/0973-7847.65330.
Leucas aspera commonly known as 'Thumbai' is distributed throughout India from the Himalayas down to Ceylon. The plant is used traditionally as an antipyretic and insecticide. Medicinally, it has been proven to possess various pharmacological activities like antifungal, antioxidant, antimicrobial, antinociceptive and cytotoxic activity. Further, studies reveal the presence of various phytochemical constituents mainly triterpenoids, oleanolic acid, ursolic acid and b-sitosterol, nicotine, sterols, glucoside, diterpenes, phenolic compounds (4-(24-hydroxy-1-oxo-5-n-propyltetracosanyl)-phenol). These studies reveal that L. aspera is a source of medicinally active compounds and have various pharmacological effects; hence, this drug encourage finding its new therapeutic uses.
糙苏通常被称为“Thumbai”，分布于印度各地，从喜马拉雅山脉直至锡兰。这种植物传统上被用作退烧药和杀虫剂。在医学上，它已被证明具有多种药理活性，如抗真菌、抗氧化、抗菌、抗伤害感受和细胞毒性活性。此外，研究表明其存在多种植物化学成分，主要有三萜类、齐墩果酸、熊果酸和β-谷甾醇、尼古丁、甾醇、糖苷、二萜类、酚类化合物（4-(24-羟基-1-氧代-5-正丙基二十四烷基)-苯酚）。这些研究表明糙苏是药用活性化合物的来源，具有多种药理作用；因此，这种药物促使人们去寻找它的新治疗用途。
