Xiang Ning, Wang Guanglin
Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu Sichuan 610041, PR China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2011 Nov;25(11):1389-92.
To review the basic researches and the clinical application of the nano-neural tissue engineering materials, especially the electrically conductive carbon nanotubes (CNT).
The literature concerning the basic and clinical researches of the conductive materials of nano-neural tissue engineering, especially the electrically conductive CNT were reviewed.
The researches of conductive materials of nano-neural tissue engineering have made some progress, the electrically conductive CNT can not only promote Schwan cells' adhension, migration, and proliferation, but also mimic the function of electric conductivity of neural myelin and enhance neurite growth and regeneration. So the electrically conductive CNT make great sense in stimulating and directing the growth of neurite and the regeneration of axons.
Because of these unique properties, the electrically conductive CNT have great advantages in peripheral nerve repair and function reconstruction, and are promising to provide a novel method for clinical peripheral nerve repair and function reconstruction after injury.
综述纳米神经组织工程材料，尤其是导电碳纳米管（CNT）的基础研究及临床应用。
回顾纳米神经组织工程导电材料，尤其是导电CNT的基础和临床研究相关文献。
纳米神经组织工程导电材料的研究取得了一定进展，导电CNT不仅能促进雪旺细胞的黏附、迁移和增殖，还能模拟神经髓鞘的导电功能，增强神经突生长和再生。因此，导电CNT在刺激和引导神经突生长及轴突再生方面具有重要意义。
由于这些独特性能，导电CNT在周围神经修复和功能重建方面具有很大优势，有望为临床周围神经损伤后修复及功能重建提供新方法。
