• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Dopaminergic neurons for Parkinson's therapy.

作者信息

Lindvall Olle

出版信息

Nat Biotechnol. 2012 Jan 9;30(1):56-8. doi: 10.1038/nbt.2077.

DOI:10.1038/nbt.2077
PMID:22231097
Abstract
摘要

相似文献

1
Dopaminergic neurons for Parkinson's therapy.用于帕金森病治疗的多巴胺能神经元。
Nat Biotechnol. 2012 Jan 9;30(1):56-8. doi: 10.1038/nbt.2077.
2
Illuminating Parkinson's therapy with optogenetics.用光遗传学照亮帕金森病的治疗之路。
Nat Biotechnol. 2015 Feb;33(2):149-50. doi: 10.1038/nbt.3140.
3
Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell.胚胎干细胞与蛋白质诱导多能干细胞多巴胺能神经元分化效率的比较研究。
PLoS One. 2014 Jan 22;9(1):e85736. doi: 10.1371/journal.pone.0085736. eCollection 2014.
4
Stem cell therapies for Parkinson's disease: are trials just around the corner?帕金森病的干细胞疗法：临床试验即将来临？
Regen Med. 2014;9(5):553-5. doi: 10.2217/rme.14.43.
5
Discovery of Novel Cell Surface Markers for Purification of Embryonic Dopamine Progenitors for Transplantation in Parkinson's Disease Animal Models.新型细胞表面标志物的发现及其用于纯化胚胎多巴胺前体细胞移植治疗帕金森病动物模型的研究。
Mol Cell Proteomics. 2018 Sep;17(9):1670-1684. doi: 10.1074/mcp.RA118.000809. Epub 2018 May 29.
6
Cell Therapies for Parkinson's Disease.帕金森病的细胞疗法
Clin Transl Sci. 2019 Mar;12(2):95-97. doi: 10.1111/cts.12612. Epub 2019 Feb 16.
7
Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons.早期发育标志物的表达预测胚胎干细胞向中脑多巴胺能神经元分化的效率。
Stem Cells Dev. 2013 Feb 1;22(3):397-411. doi: 10.1089/scd.2012.0238. Epub 2012 Sep 20.
8
Implications of Parkinson's disease pathophysiology for the development of cell replacement strategies and drug discovery in neurodegenerative diseases.帕金森病发病机制对神经退行性疾病中细胞替代策略和药物发现的影响。
CNS Neurol Disord Drug Targets. 2012 Nov 1;11(7):907-20. doi: 10.2174/1871527311201070907.
9
Improvement of neurological dysfunctions in aphakia mice, a model of Parkinson's disease, after transplantation of ES cell-derived dopaminergic neuronal precursors.在移植胚胎干细胞来源的多巴胺能神经元前体细胞后，帕金森病模型无晶状体小鼠神经功能障碍的改善。
Methods Mol Biol. 2014;1213:285-91. doi: 10.1007/978-1-4939-1453-1_23.
10
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.人胚胎干细胞衍生的多巴胺神经元在帕金森病动物模型中有效移植。
Nature. 2011 Nov 6;480(7378):547-51. doi: 10.1038/nature10648.

引用本文的文献

1
Chemical and Biological Molecules Involved in Differentiation, Maturation, and Survival of Dopaminergic Neurons in Health and Parkinson's Disease: Physiological Aspects and Clinical Implications.参与健康及帕金森病中多巴胺能神经元分化、成熟和存活的化学及生物分子：生理方面及临床意义
Biomedicines. 2021 Jun 29;9(7):754. doi: 10.3390/biomedicines9070754.
2
Neural tube patterning: from a minimal model for rostrocaudal patterning toward an integrated 3D model.神经管模式形成：从用于头尾模式形成的最小模型到综合三维模型
iScience. 2021 May 20;24(6):102559. doi: 10.1016/j.isci.2021.102559. eCollection 2021 Jun 25.
3
Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior.

本文引用的文献

1
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.人胚胎干细胞衍生的多巴胺神经元在帕金森病动物模型中有效移植。
Nature. 2011 Nov 6;480(7378):547-51. doi: 10.1038/nature10648.
2
Cell therapeutics in Parkinson's disease.帕金森病的细胞治疗。
Neurotherapeutics. 2011 Oct;8(4):539-48. doi: 10.1007/s13311-011-0069-6.
3
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplants.血清素能神经元介导帕金森病患者神经移植后的运动障碍副作用。
多巴胺能神经元共传递谷氨酸，从突触到回路再到行为。
Front Neural Circuits. 2021 May 19;15:665386. doi: 10.3389/fncir.2021.665386. eCollection 2021.
4
Human Mesenchymal Stromal Cells Unveil an Unexpected Differentiation Potential toward the Dopaminergic Neuronal Lineage.人骨髓间充质干细胞揭示了向多巴胺能神经元谱系的意外分化潜能。
Int J Mol Sci. 2020 Sep 9;21(18):6589. doi: 10.3390/ijms21186589.
5
Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the approach.营养基因组学作为研究饮食对衰老及与年龄相关疾病影响的工具：方法
Genes Nutr. 2019 May 2;14:12. doi: 10.1186/s12263-019-0638-6. eCollection 2019.
6
Efficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform.高效生成人胚胎干细胞来源的中脑多巴胺能神经元的全定义、可扩展的 3D 生物材料平台。
Sci Rep. 2017 Jan 16;7:40573. doi: 10.1038/srep40573.
7
Stem and Progenitor Cell-Based Therapy of the Central Nervous System: Hopes, Hype, and Wishful Thinking.基于干细胞和祖细胞的中枢神经系统治疗：希望、炒作与一厢情愿的想法
Cell Stem Cell. 2016 Feb 4;18(2):174-88. doi: 10.1016/j.stem.2016.01.012.
8
Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson's disease.丝裂霉素处理的未分化胚胎干细胞作为帕金森病小鼠模型中的一种安全有效的治疗策略。
Front Cell Neurosci. 2015 Apr 8;9:97. doi: 10.3389/fncel.2015.00097. eCollection 2015.
9
Fetal stem cell transplantation: Past, present, and future.胎儿干细胞移植：过去、现在与未来。
World J Stem Cells. 2014 Sep 26;6(4):404-20. doi: 10.4252/wjsc.v6.i4.404.
10
Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease.干细胞疗法。利用分化的多能干细胞作为替代疗法来治疗疾病。
Science. 2014 Aug 22;345(6199):1247391. doi: 10.1126/science.1247391.
Sci Transl Med. 2010 Jun 30;2(38):38ra46. doi: 10.1126/scitranslmed.3000976.
4
Efficient derivation of functional floor plate tissue from human embryonic stem cells.高效地从人类胚胎干细胞中获得功能性基板组织。
Cell Stem Cell. 2010 Apr 2;6(4):336-347. doi: 10.1016/j.stem.2010.03.001.
5
Stem cells in human neurodegenerative disorders--time for clinical translation?人类神经退行性疾病中的干细胞——临床转化的时机？
J Clin Invest. 2010 Jan;120(1):29-40. doi: 10.1172/JCI40543.
6
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells.通过胚胎干细胞中Lmx1a的表达高效生成中脑多巴胺能神经元。
Proc Natl Acad Sci U S A. 2009 May 5;106(18):7613-8. doi: 10.1073/pnas.0902396106. Epub 2009 Apr 21.
7
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling.通过双重抑制SMAD信号通路实现人胚胎干细胞和诱导多能干细胞的高效神经转化。
Nat Biotechnol. 2009 Mar;27(3):275-80. doi: 10.1038/nbt.1529. Epub 2009 Mar 1.
8
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease.帕金森病长期胚胎黑质移植中的路易小体样病理改变。
Nat Med. 2008 May;14(5):504-6. doi: 10.1038/nm1747. Epub 2008 Apr 6.
9
Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells.从人类胚胎干细胞高效大规模生成功能性多巴胺神经元。
Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3392-7. doi: 10.1073/pnas.0712359105. Epub 2008 Feb 27.
10
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.通过与端粒酶永生化中脑星形胶质细胞共培养富集的人胚胎干细胞衍生多巴胺能神经元的功能植入。
Nat Med. 2006 Nov;12(11):1259-68. doi: 10.1038/nm1495. Epub 2006 Oct 22.