Sipos Enikö, Stifter Eva, Menapace Rupert
Department of Ophthalmology and Optometry, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Int Ophthalmol. 2011 Dec;31(6):453-60. doi: 10.1007/s10792-011-9497-x. Epub 2012 Jan 10.
The purpose of this study was to evaluate if administration of artificial tears of high or low-viscosity improve cataract patients' satisfaction and postoperative pain after cataract surgery. Thirty consecutive patients undergoing bilateral cataract surgery under topical anesthesia were enrolled prospectively. Administration of the following postoperative therapies was randomized: for all participants, one eye was treated with "instant vision" (IV) therapy alone (IV-alone), i.e., this eye remained uncovered. In group 1 (n = 11), the second eye received IV therapy with Hylo-Comod(®) (HC) eye drops; in group 2 (n = 9), IV with Vidisic(®) (VS) eye drops; in group 3 (n = 10), an ointment bandage (OB). Postoperative satisfaction, pain scores, visual acuity, intraocular pressure, tear break-up time and postoperative corneal changes were compared. Group 1: No clear preference was observed for any of the methods concerning subjective satisfaction. Group 2: 100% of patients preferred IV + VS therapy. Group 3: Patients' postoperative satisfaction with OB therapy was 89%. Concerning postoperative pain perception, no significant differences were found between IV therapy alone and the IV-combination therapies. Significant differences in pain perception (P < 0.042) were measured between IV and OB in the first 8 h postoperatively. Ten hours postoperatively and beyond, there were no significant differences in pain scores (P > 0.05). Pain perception was significantly lower with OB when compared to IV-alone or IV-combination therapies using artificial tears. This result was verified by OB's 89% patient satisfaction level. Low-viscosity artificial tears showed no significant subjective benefits for the patients; patient satisfaction was greatest (100%) with a high-viscosity tear substitute.
本研究的目的是评估使用高粘度或低粘度人工泪液是否能提高白内障患者在白内障手术后的满意度并减轻术后疼痛。前瞻性纳入了30例接受表面麻醉下双侧白内障手术的连续患者。术后治疗方法随机分配:对于所有参与者,一只眼睛仅接受“即时视力”(IV)治疗(单独使用IV),即该眼睛不覆盖。在第1组(n = 11)中,另一只眼睛接受含海露(®)(HC)滴眼液的IV治疗;在第2组(n = 9)中,接受含维地息(®)(VS)滴眼液的IV治疗;在第3组(n = 10)中,使用眼膏绷带(OB)。比较术后满意度、疼痛评分、视力、眼压、泪膜破裂时间和术后角膜变化。第1组:在主观满意度方面,未观察到对任何一种方法有明显偏好。第2组:100%的患者更喜欢IV + VS治疗。第3组:患者对OB治疗的术后满意度为89%。关于术后疼痛感知,单独使用IV治疗与IV联合治疗之间未发现显著差异。术后前8小时,IV与OB之间的疼痛感知存在显著差异(P < 0.042)。术后10小时及以后,疼痛评分无显著差异(P > 0.05)。与单独使用IV或使用人工泪液的IV联合治疗相比,OB的疼痛感知明显更低。这一结果通过OB 89%的患者满意度得到了验证。低粘度人工泪液对患者没有明显的主观益处;高粘度泪液替代品的患者满意度最高(100%)。