Kliks S
Cancer Research Institute, University of California, School of Medicine, San Francisco 94143-0128.
AIDS Res Hum Retroviruses. 1990 Aug;6(8):993-8. doi: 10.1089/aid.1990.6.993.
Antibody-dependent enhancement of certain virus infections can occur in cells expressing Fc receptors. This mechanism plays an important pathogenetic role in the development of complications associated with dengue virus infection, including dengue hemorrhagic infection and dengue shock syndrome. The virulence of the virus, characterized by the ability to infect Fc receptor-bearing monocytes also influences the development of these severe illnesses.
在表达Fc受体的细胞中，某些病毒感染可出现抗体依赖性增强现象。该机制在与登革病毒感染相关的并发症（包括登革出血热感染和登革休克综合征）的发生发展中发挥着重要的致病作用。以感染携带Fc受体的单核细胞的能力为特征的病毒毒力也会影响这些严重疾病的发生发展。
