[噻吩烷对实验性四氯化碳诱导肝炎大鼠的肝保护作用]
[Hepatoprotective effect of thiophane in rats with experimental carbon tetrachloride-induced hepatitis].
作者信息
Smol'iakova V I, Plotnikov M B, Chernysheva G A, Ivanov I S, Prosenko A E, Kandalintseva N V
出版信息
Eksp Klin Farmakol. 2011;74(8):37-40.
PMID:22232913
Abstract
A hepatoprotective effect of thiophan was studied on the model of carbon tetrachloride-induced hepatitis in rats. Therapeutic administration of thiophan repairs the antitoxic function of liver, normalizes cytolysis marker activity, and improves the synthetic function of liver and the carbohydrate and lipid metabolism. The hepatoprotective activity of thiophan is similar to effect of silimarin.
摘要
研究了硫喷妥对四氯化碳诱导的大鼠肝炎模型的保肝作用。硫喷妥的治疗性给药可修复肝脏的抗毒功能，使细胞溶解标志物活性正常化，并改善肝脏的合成功能以及碳水化合物和脂质代谢。硫喷妥的保肝活性与水飞蓟宾的作用相似。
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