Zoccali M, Fichera A
Department of Surgery, University of Chicago Medical Center, Chicago, IL 60637, USA.
Minerva Chir. 2011 Dec;66(6):589-601.
Since the introduction of laparoscopic surgery in the management of colorectal disease in the early '90s, minimally invasive techniques have gained popularity. While good quality studies have been published in the literature on laparoscopy for colorectal cancer, evidence supporting the use of minimally invasive surgery for inflammatory bowel disease is lacking. This patient population represents a challenge to the colorectal surgeon even in conventional open surgery and this has limited the widespread application of minimally invasive techniques especially in Crohn's disease. Laparoscopic ileocecal resection for Crohn's disease is the most performed minimally invasive procedure in the field of inflammatory bowel disease, with promising short-term outcomes but with still some concerns related to prolonged operative times and overall costs. For ulcerative colitis the magnitude of restorative procedures has also restricted the use of minimally invasive approaches to highly specialized tertiary referral centers. The benefits of performing restorative procedures laparoscopically for ulcerative colitis are less obvious based on the limited reports available in the literature with adequate follow-up for assessing long-term outcomes, and controversies still remains about the need for a staged approach in the era of biologic therapy. Nevertheless, surgeons are actively working in an effort to obviate to the current technical limitations of laparoscopy, and to further minimize surgical trauma. In this manuscript we will present the current evidence supporting the use of laparoscopy and minimally invasive techniques in inflammatory bowel disease and present the future direction of development and research.
自20世纪90年代初腹腔镜手术被引入结直肠疾病的治疗以来,微创技术越来越受欢迎。虽然关于腹腔镜治疗结直肠癌的高质量研究已在文献中发表,但支持将微创手术用于炎症性肠病的证据仍然不足。即使在传统的开放手术中,这类患者群体对于结直肠外科医生来说也是一个挑战,这限制了微创技术的广泛应用,尤其是在克罗恩病中。在炎症性肠病领域,腹腔镜回盲部切除术是针对克罗恩病实施最多的微创手术,其短期效果良好,但仍存在一些与手术时间延长和总体费用相关的问题。对于溃疡性结肠炎,修复性手术的规模也限制了微创方法仅在高度专业化的三级转诊中心使用。基于文献中可获得的有限报告以及用于评估长期结果的充分随访,腹腔镜下对溃疡性结肠炎进行修复性手术的益处尚不明显,并且在生物治疗时代是否需要分期手术仍存在争议。尽管如此,外科医生们仍在积极努力消除腹腔镜手术目前的技术限制,并进一步减少手术创伤。在本手稿中,我们将展示支持在炎症性肠病中使用腹腔镜和微创技术的现有证据,并介绍未来的发展和研究方向。