RTI International, Research Triangle Park, NC, USA.
Subst Abuse Treat Prev Policy. 2012 Jan 10;7:1. doi: 10.1186/1747-597X-7-1.
With HIV prevalence estimated at 20% among female injecting drug users (IDUs) in St. Petersburg, Russia, there is a critical need to address the HIV risks of this at-risk population. This study characterized HIV risks associated with injecting drug use and sex behaviors and assessed the initial feasibility and efficacy of an adapted Woman-Focused intervention, the Women's CoOp, relative to a Nutrition control to reduce HIV risk behaviors among female IDUs in an inpatient detoxification drug treatment setting.
Women (N = 100) were randomized into one of two one-hour long intervention conditions--the Woman-Focused intervention (n = 51) or a time and attention-matched Nutrition control condition (n = 49).
The results showed that 57% of the participants had been told that they were HIV-positive. At 3-month follow-up, both groups showed reduced levels of injecting frequency. However, participants in the Woman-Focused intervention reported, on average, a lower frequency of partner impairment at last sex act and a lower average number of unprotected vaginal sex acts with their main sex partner than the Nutrition condition.
The findings suggest that improvements in sexual risk reduction are possible for these at-risk women and that more comprehensive treatment is needed to address HIV and drug risks in this vulnerable population.
在俄罗斯圣彼得堡，女性注射吸毒者（IDU）中的 HIV 感染率估计为 20%，因此迫切需要解决这一高危人群的 HIV 风险。本研究描述了与注射吸毒和性行为相关的 HIV 风险，并评估了经改编的针对女性的干预措施（妇女合作社）与营养控制相比在减少女性 IDU 住院戒毒治疗环境中的 HIV 风险行为方面的初步可行性和效果。
将 100 名女性随机分配到两种干预条件之一：妇女重点干预（n = 51）或时间和注意力匹配的营养控制条件（n = 49）。
结果显示，57%的参与者被告知 HIV 呈阳性。在 3 个月的随访中，两组的注射频率均有所降低。然而，与营养条件相比，妇女重点干预组的参与者在最近一次性行为中报告的伴侣受损频率较低，与主要性伴侣发生的无保护阴道性行为的平均次数也较少。
研究结果表明，这些高危女性有可能减少性风险，需要更全面的治疗来解决这一弱势群体的 HIV 和药物风险。
