Bone Joint J. 2013 Aug;95-B(8):1045-51. doi: 10.1302/0301-620X.95B8.31811.
The purpose of this study was twofold: first, to determine whether the five-year results of hip resurfacing arthroplasty (HRA) in Canada justified the continued use of HRA; and second, to identify whether greater refinement of patient selection was warranted. This was a retrospective cohort study that involved a review of 2773 HRAs performed between January 2001 and December 2008 at 11 Canadian centres. Cox's proportional hazards models were used to analyse the predictors of failure of HRA. Kaplan-Meier survival analysis was performed to predict the cumulative survival rate at five years. The factors analysed included age, gender, body mass index, pre-operative hip pathology, surgeon's experience, surgical approach, implant sizes and implant types. The most common modes of failure were also analysed. The 2773 HRAs were undertaken in 2450 patients: 2127 in men and 646 in women. The mean age at operation was 50.5 years (sd 8.72; 18 to 82) and mean follow-up was 3.4 years (sd 2.1; 2.0 to 10.1). At the last follow-up a total of 101 HRAs (3.6%) required revision. Using revision for all causes of failure as the endpoint, Kaplan-Meier survival analysis showed a cumulative survival of 96.4% (95% confidence interval (CI) 96.1 to 96.9) at five years. With regard to gender, the five-year overall survival was 97.4% in men (95% CI 97.1 to 97.7) and 93.6% in women (95% CI 92.6 to 94.6). Female gender, smaller femoral components, specific implant types and a diagnosis of childhood hip problems were associated with higher rates of failure. The most common cause of failure was fracture of the femoral neck, followed by loosening of the femoral component. The failure rates of HRA at five years justify the ongoing use of this technique in men. Female gender is an independent predictor of failure, and a higher failure rate at five years in women leads the authors to recommend this technique only in exceptional circumstances for women.
第一,确定加拿大髋关节表面置换术(HRA)的五年结果是否证明继续使用 HRA 是合理的;第二,确定是否需要进一步完善患者选择。这是一项回顾性队列研究,涉及对 2001 年 1 月至 2008 年 12 月在加拿大 11 个中心进行的 2773 例 HRA 的回顾。采用 Cox 比例风险模型分析 HRA 失败的预测因素。进行 Kaplan-Meier 生存分析以预测五年累积生存率。分析的因素包括年龄、性别、体重指数、术前髋关节病变、外科医生的经验、手术入路、植入物大小和植入物类型。还分析了最常见的失效模式。这 2773 例 HRA 是在 2450 例患者中进行的:2127 例男性,646 例女性。手术时的平均年龄为 50.5 岁(标准差 8.72;18 至 82 岁),平均随访时间为 3.4 年(标准差 2.1;2.0 至 10.1 年)。在最后一次随访时,共有 101 例 HRA(3.6%)需要翻修。以所有原因的失败为终点,Kaplan-Meier 生存分析显示,五年时的累积生存率为 96.4%(95%置信区间 96.1%至 96.9%)。关于性别,男性五年总生存率为 97.4%(95%置信区间 97.1%至 97.7%),女性为 93.6%(95%置信区间 92.6%至 94.6%)。女性、较小的股骨部件、特定的植入物类型和儿童髋关节问题的诊断与较高的失败率相关。最常见的失败原因是股骨颈骨折,其次是股骨部件松动。五年时 HRA 的失败率证明了该技术在男性中的持续使用是合理的。女性是失败的独立预测因素,女性五年时的失败率较高,导致作者建议仅在特殊情况下对女性使用该技术。