相似文献
1
Genetic and molecular characterization of uveal melanoma cell lines.葡萄膜黑色素瘤细胞系的遗传和分子特征。
Pigment Cell Melanoma Res. 2012 Mar;25(2):182-7. doi: 10.1111/j.1755-148X.2012.00971.x. Epub 2012 Feb 2.
2
Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.葡萄膜黑色素瘤中频繁出现但尚未报道的 GNAQ 和 GNA11 突变。
Pathol Oncol Res. 2019 Oct;25(4):1319-1325. doi: 10.1007/s12253-017-0371-7. Epub 2017 Dec 5.
3
Genetic and clinico-pathologic analysis of metastatic uveal melanoma.葡萄膜黑色素瘤转移的遗传及临床病理分析。
Mod Pathol. 2014 Feb;27(2):175-83. doi: 10.1038/modpathol.2013.138. Epub 2013 Jul 26.
4
Bioinformatics analysis of GNAQ, GNA11, BAP1, SF3B1,SRSF2, EIF1AX, PLCB4, and CYSLTR2 genes and their role in the pathogenesis of Uveal Melanoma.GNAQ、GNA11、BAP1、SF3B1、SRSF2、EIF1AX、PLCB4 和 CYSLTR2 基因的生物信息学分析及其在葡萄膜黑色素瘤发病机制中的作用。
Ophthalmic Genet. 2021 Dec;42(6):732-743. doi: 10.1080/13816810.2021.1961280. Epub 2021 Aug 6.
5
Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner.联合使用小分子 MEK 和 PI3K 抑制剂可增强依赖突变 GNAQ 和 GNA11 的葡萄膜黑色素瘤细胞死亡。
Clin Cancer Res. 2012 Aug 15;18(16):4345-55. doi: 10.1158/1078-0432.CCR-11-3227. Epub 2012 Jun 25.
6
The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan.GNAQ或GNA11突变率在日本葡萄膜黑色素瘤病例中的作用。
Appl Immunohistochem Mol Morphol. 2018 Oct;26(9):658-663. doi: 10.1097/PAI.0000000000000505.
7
Mutations in GNA11 in uveal melanoma.GNA11 基因突变与葡萄膜黑色素瘤。
N Engl J Med. 2010 Dec 2;363(23):2191-9. doi: 10.1056/NEJMoa1000584. Epub 2010 Nov 17.
8
Molecular and immunohistochemical analyses of uveal melanoma patient cohort.葡萄膜黑色素瘤患者队列的分子和免疫组织化学分析。
Melanoma Res. 2019 Jun;29(3):248-253. doi: 10.1097/CMR.0000000000000523.
9
Prognostic impact of chromosomal aberrations and GNAQ, GNA11 and BAP1 mutations in uveal melanoma.葡萄膜黑色素瘤中染色体畸变以及GNAQ、GNA11和BAP1突变的预后影响
Acta Ophthalmol. 2018 Feb;96(1):31-38. doi: 10.1111/aos.13452. Epub 2017 Apr 26.
10
The phosphoinositide 3-kinase α selective inhibitor BYL719 enhances the effect of the protein kinase C inhibitor AEB071 in GNAQ/GNA11-mutant uveal melanoma cells.磷酸肌醇 3-激酶 α 选择性抑制剂 BYL719 增强蛋白激酶 C 抑制剂 AEB071 在 GNAQ/GNA11 突变性葡萄膜黑素瘤细胞中的作用。
Mol Cancer Ther. 2014 May;13(5):1044-53. doi: 10.1158/1535-7163.MCT-13-0550. Epub 2014 Feb 21.
引用本文的文献
1
Allele-specific depletion of via siRNA or an rAAV2-shRNA vector induces selective toxicity in uveal melanoma cells.通过小干扰RNA（siRNA）或重组腺相关病毒2型短发夹RNA（rAAV2-shRNA）载体进行等位基因特异性缺失，可在葡萄膜黑色素瘤细胞中诱导选择性毒性。
Mol Ther Oncol. 2025 Jul 17;33(3):201020. doi: 10.1016/j.omton.2025.201020. eCollection 2025 Sep 18.
2
Targeting ocular malignancies using a novel light-activated virus-like drug conjugate.使用新型光激活病毒样药物偶联物靶向眼部恶性肿瘤。
Adv Ophthalmol Pract Res. 2024 Dec 3;5(1):49-57. doi: 10.1016/j.aopr.2024.12.001. eCollection 2025 Feb-Mar.
3
PLEK2: a potential biomarker for metastasis and prognostic evaluation in uveal melanoma.PLEK2：葡萄膜黑色素瘤转移和预后评估的潜在生物标志物。
Front Med (Lausanne). 2024 Dec 2;11:1507576. doi: 10.3389/fmed.2024.1507576. eCollection 2024.
4
The Phenotypical Characterization of Dual-Nature Hybrid Cells in Uveal Melanoma.葡萄膜黑色素瘤中双性质杂交细胞的表型特征
Cancers (Basel). 2024 Sep 22;16(18):3231. doi: 10.3390/cancers16183231.
5
The Chick Chorioallantoic Membrane as a Xenograft Model for the Quantitative Analysis of Uveal Melanoma Metastasis in Multiple Organs.鸡胚尿囊膜异种移植模型用于多种器官中葡萄膜黑色素瘤转移的定量分析。
Cells. 2024 Jul 9;13(14):1169. doi: 10.3390/cells13141169.
6
Protein and mRNA Expression in Uveal Melanoma Cell Lines Are Related to GNA and BAP1 Mutation Status.葡萄膜黑色素瘤细胞系中的蛋白和 mRNA 表达与 GNA 和 BAP1 突变状态相关。
Invest Ophthalmol Vis Sci. 2024 Jul 1;65(8):37. doi: 10.1167/iovs.65.8.37.
7
Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy.基于基因网络和集成模型的选择，预测具有低组织损伤风险的肿瘤相关抗原，用于靶向免疫治疗。
J Immunother Cancer. 2024 May 9;12(5):e008104. doi: 10.1136/jitc-2023-008104.
8
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies.GPATCH8 调节血液系统恶性肿瘤中突变 SF3B1 的剪接错误和致病性。
Mol Cell. 2024 May 16;84(10):1886-1903.e10. doi: 10.1016/j.molcel.2024.04.006. Epub 2024 Apr 29.
9
Quercetin Impairs the Growth of Uveal Melanoma Cells by Interfering with Glucose Uptake and Metabolism.槲皮素通过干扰葡萄糖摄取和代谢来抑制葡萄膜黑色素瘤细胞的生长。
Int J Mol Sci. 2024 Apr 12;25(8):4292. doi: 10.3390/ijms25084292.
10
From Molecular Biology to Novel Immunotherapies and Nanomedicine in Uveal Melanoma.从分子生物学到葡萄膜黑色素瘤的新型免疫疗法和纳米医学。
Curr Oncol. 2024 Feb 1;31(2):778-800. doi: 10.3390/curroncol31020058.
本文引用的文献
1
Uveal melanoma: trends in incidence, treatment, and survival.葡萄膜黑色素瘤：发病趋势、治疗方法和生存率。
Ophthalmology. 2011 Sep;118(9):1881-5. doi: 10.1016/j.ophtha.2011.01.040. Epub 2011 Jun 24.
2
Pathways to melanoma.黑色素瘤的发病途径
Semin Cutan Med Surg. 2010 Dec;29(4):210-7. doi: 10.1016/j.sder.2010.10.004.
3
Mutations in GNA11 in uveal melanoma.GNA11 基因突变与葡萄膜黑色素瘤。
N Engl J Med. 2010 Dec 2;363(23):2191-9. doi: 10.1056/NEJMoa1000584. Epub 2010 Nov 17.
4
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.人类癌症中exon 4 KRAS 突变的基因组和生物学特征。
Cancer Res. 2010 Jul 15;70(14):5901-11. doi: 10.1158/0008-5472.CAN-10-0192. Epub 2010 Jun 22.
5
Evaluation of the mTOR pathway in ocular (uvea and conjunctiva) melanoma.眼葡萄膜（虹膜和脉络膜）黑色素瘤中 mTOR 通路的评估。
Melanoma Res. 2010 Apr;20(2):107-17. doi: 10.1097/CMR.0b013e32832ccd09.
6
Novel cell lines derived by long-term culture of primary uveal melanomas.通过原发性葡萄膜黑色素瘤长期培养获得的新型细胞系。
Ophthalmologica. 2009;223(3):196-201. doi: 10.1159/000201566. Epub 2009 Feb 12.
7
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi.葡萄膜黑色素瘤和蓝色痣中GNAQ的频繁体细胞突变。
Nature. 2009 Jan 29;457(7229):599-602. doi: 10.1038/nature07586. Epub 2008 Dec 10.
8
The T1799A point mutation is present in posterior uveal melanoma.T1799A 点突变存在于后葡萄膜黑色素瘤中。
Br J Cancer. 2008 Nov 18;99(10):1673-7. doi: 10.1038/sj.bjc.6604731. Epub 2008 Nov 4.
9
Authenticating cell lines in ophthalmic research laboratories.眼科研究实验室中细胞系的鉴定
Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4697-701. doi: 10.1167/iovs.08-2324. Epub 2008 Aug 8.
10
Pyrophosphorolysis detects B-RAF mutations in primary uveal melanoma.焦磷酸解反应检测原发性葡萄膜黑色素瘤中的B-RAF突变。
Invest Ophthalmol Vis Sci. 2008 Jan;49(1):23-7. doi: 10.1167/iovs.07-0722.
Zotero 插件